BV421-DRB1*04:01/Human Tyrosinase (ALHIYMDGTMSQVQGSA) MHC Tetramer (CAT#: MHC-YF1419)

• Allele
• DRB1*04:01

• Class
• Class II

• MHC Species
• Human

• Antigen
• Tyrosinase

• Peptide
• ALHIYMDGTMSQVQGSA

• Range
• 365-381

• Conjugate
• BV421

• Application
• FCM

• Antigen Introduction
• The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

• Alternative Names
• TYR; Tyrosinase; ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3

• Gene ID
• 7299

• UniProt ID
• P14679

Select a product category from the dropdown menu below to view related products.