Tyrosinase

Anti-Tyrosinase Products

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Recombinant Mouse Anti-Human TYR Antibody (clone U312) (MOB-0343MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
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A*02:01/Human Tyrosinase (YMDGTMSQV) MHC Tetramer (MHC-LC013)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: YMDGTMSQV
- Conjugate: BV421
Compare

PE-B*07:02/Human Tyrosinase (LPWHRLFLL) MHC Tetramer (MHC-LC015)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

APC-B*07:02/Human Tyrosinase (LPWHRLFLL) MHC Tetramer (MHC-LC016)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: APC
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PE-A*24:02/Human Tyrosinase (AFLPWHRLF) MHC Tetramer (MHC-LC155)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: AFLPWHRLF
- Conjugate: PE
Compare

APC-A*24:02/Human Tyrosinase (AFLPWHRLF) MHC Tetramer (MHC-LC156)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: AFLPWHRLF
- Conjugate: APC
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A*0201/Human Tyrosinase (YMDGTMSQV) MHC Tetramer (MHC-LC791)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: YMDGTMSQV
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PE-A*02:01/Human TYR (MLLAVLYCL) MHC Tetramer (MHC-LC2226)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: MLLAVLYCL
- Conjugate: PE
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PE-A*02:01/Human TYR (YMNGTMSQV) MHC Tetramer (MHC-LC2230)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMNGTMSQV
- Conjugate: PE
Compare

PE-DRB1*04:01/Human TYR (NILLSNAPLGPQFP) MHC Tetramer (MHC-LC2451)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: NILLSNAPLGPQFP
- Conjugate: PE
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PE-DRB1*04:01/Human TYR (QNILLSNAPLGPQFP) MHC Tetramer (MHC-LC2452)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: QNILLSNAPLGPQFP
- Conjugate: PE
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PE-B*07:02/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2548)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
Compare

PE-DRB1*04:01/Human TYR (SYLQDSDPDSFQD) MHC Tetramer (MHC-LC2453)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: SYLQDSDPDSFQD
- Conjugate: PE
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PE-DRB1*04:01/Human TYR (YLQDSDPDSFQD) MHC Tetramer (MHC-LC2454)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: YLQDSDPDSFQD
- Conjugate: PE
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PE-A*02:01/Human TYR (ALLAGLVSL) MHC Tetramer (MHC-LC2901)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALLAGLVSL
- Conjugate: PE
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PE-A*02:01/Human TYR (ALLAGLVSLL) MHC Tetramer (MHC-LC2902)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALLAGLVSLL
- Conjugate: PE
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PE-A*02:01/Human TYR (AMVGAVLTA) MHC Tetramer (MHC-LC2905)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: AMVGAVLTA
- Conjugate: PE
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PE-B*07:02/Human TYR (IPIGTYGQM) MHC Tetramer (MHC-LC3012)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: IPIGTYGQM
- Conjugate: PE
Compare

APC-B*07:02/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC3017)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: APC
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PE-A*11:01/Human TYR (QTSAGHFPR) MHC Tetramer (MHC-LC3023)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: QTSAGHFPR
- Conjugate: PE
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PE-A*03:01/Human TYR (SIFEQWLRR) MHC Tetramer (MHC-LC3024)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SIFEQWLRR
- Conjugate: PE
Compare

PE-DRB1*04:01/Human TYR (ALHIYMDGTMSQVQGSA) MHC Tetramer (MHC-LC3196)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: PE
Compare

PE-DRB1*04:04/Human TYR (ALHIYMDGTMSQVQGSA) MHC Tetramer (MHC-LC3197)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: PE
Compare

PE-DRB1*04:01/Human TYR (ALHIYMNGTMSQVQGSA) MHC Tetramer (MHC-LC3198)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMNGTMSQVQGSA
- Conjugate: PE
Compare

PE-DRB1*04:04/Human TYR (ALHIYMNGTMSQVQGSA) MHC Tetramer (MHC-LC3199)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMNGTMSQVQGSA
- Conjugate: PE
Compare

PE-DRB1*04:01/Human TYR (DYSYLQDSDPDSFQD) MHC Tetramer (MHC-LC3200)
- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: DYSYLQDSDPDSFQD
- Conjugate: PE
Compare

PE-A*24:02/Human TYR (AFLPWHRLF) MHC Tetramer (MHC-LC3294)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: AFLPWHRLF
- Conjugate: PE
Compare

PE-A*01:01/Human TYR (KCDICTDEY) MHC Tetramer (MHC-LC4411)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: KCDICTDEY
- Conjugate: PE
Compare

Mouse Anti-TYR Recombinant Antibody (clone C2-B5) (MRO-1543-CN)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IF, IHC, FC
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Rabbit Anti-TYR Recombinant Antibody (clone JA52-11) (MRO-1544-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC
Compare

DRB1*04:01/Human Tyrosinase (ALHIYMDGTMSQVQGSA) MHC Tetramer (MHC-YF811)
- Class: Class II
- Antigen: Tyrosinase
- Peptide: ALHIYMDGTMSQVQGSA
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (B12) (KIH) (VS-0622-YF5875)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (di111) (KIH) (VS-0622-YF5876)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (T43) (KIH) (VS-0622-YF5877)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

PE-A*02:01/Human TYR (FLLRWEQEI) MHC Tetramer (MHC-LC2909)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLLRWEQEI
- Conjugate: PE
Compare

APC-DRB1*04:01/Human Tyrosinase (ALHIYMDGTMSQVQGSA) MHC Tetramer (MHC-YF963)
- Class: Class II
- Antigen: Tyrosinase
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: APC
Compare

PE-A*02:01/Human TYR (FLPWHRLFL) MHC Tetramer (MHC-LC2910)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLPWHRLFL
- Conjugate: PE
Compare

PE-A*02:01/Human TYR (FLPWHRLFLL) MHC Tetramer (MHC-LC2911)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLPWHRLFLL
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (B12) (ZIP-Fos/ZIP-Jun) (VS-0622-YF459)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

BV421-B*07:02/Human Tyrosinase (LPWHRLFLL) MHC Tetramer (MHC-LC017)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: BV421
Compare

PE-A*02:01/Human TYR (LLAGLVSLL) MHC Tetramer (MHC-LC2919)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLAGLVSLL
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (di111) (ZIP-Fos/ZIP-Jun) (VS-0622-YF460)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

PE-A*01:01/Human Tyrosinase (KSDICTDEY) MHC Tetramer (MHC-LC018)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: KSDICTDEY
- Conjugate: PE
Compare

PE-A*02:01/Human TYR (LLAVLYCLL) MHC Tetramer (MHC-LC2920)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLAVLYCLL
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (T43) (ZIP-Fos/ZIP-Jun) (VS-0622-YF461)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

APC-A*01:01/Human Tyrosinase (KSDICTDEY) MHC Tetramer (MHC-LC019)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: KSDICTDEY
- Conjugate: APC
Compare

PE-A*02:01/Human TYR (LLWSFQTSA) MHC Tetramer (MHC-LC2922)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLWSFQTSA
- Conjugate: PE
Compare

BV421-A*01:01/Human Tyrosinase (KSDICTDEY) MHC Tetramer (MHC-LC020)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: KSDICTDEY
- Conjugate: BV421
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (ZIP-Fos/ZIP-Jun) (VS-0622-YF462) (VS-0622-YF462)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

PE-A*02:01/Human TYR (RIWSWLLGA) MHC Tetramer (MHC-LC2927)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: RIWSWLLGA
- Conjugate: PE
Compare

PE-A*02:01/Human TYR (VLTALLAGL) MHC Tetramer (MHC-LC2936)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: VLTALLAGL
- Conjugate: PE
Compare

Human Anti-Tyrosinase Recombinant Soluble TCR (clone UG6) (scTCR-1211YC-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

PE-A*11:01/Human TYR (YMVPFIPLYR) MHC Tetramer (MHC-LC3032)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMVPFIPLYR
- Conjugate: PE
Compare

PE-B*35:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2514)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

A*02:01/Human Tyrosinase (YMDGTMSQV) MHC Monomer (MHC-YF230)
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: YMDGTMSQV
- Conjugate: Biotin
Compare

Rabbit Anti-TYR Polyclonal Antibody (MRO-2248-CN) (MRO-2248-CN)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
Compare

PE-B*51:01/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2549)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
Compare

PE-B*51:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2515)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

PE-B*53:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2516)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (TA4) (KIH) (VS-0622-YF7914)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (clone B12) (scTCR-460CQ-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

PE-B*53:01/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2550)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (clone di111) (scTCR-461CQ-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

APC-A*02:01/Human TYR (MLLAVLYCL) MHC Tetramer (MHC-LC2626)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: MLLAVLYCL
- Conjugate: APC
Compare

PE-B*54:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2517)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (TD6) (KIH) (VS-0622-YF7915)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (clone T43) (scTCR-462CQ-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

APC-A*02:01/Human TYR (YMNGTMSQV) MHC Tetramer (MHC-LC2630)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMNGTMSQV
- Conjugate: APC
Compare

PE-B*07:02/Human TYR (SPASFFSSW) MHC Tetramer (MHC-LC2533)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SPASFFSSW
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (UG6) (KIH) (VS-0622-YF7916)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (scTCR-463CQ-S(P)) (scTCR-463CQ-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

DRB1*04:01/Human tyrosinase (ALHIYMDGTMSQVQGSA) MHC Monomer (MHC-YF056)
- Class: Class II
- Antigen: tyrosinase
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: Biotin
Compare

PE-B*51:01/Human TYR (DPDSFQDYI) MHC Tetramer (MHC-LC2464)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPDSFQDYI
- Conjugate: PE
Compare

PE-B*51:01/Human TYR (DPIFLLHHA) MHC Tetramer (MHC-LC2465)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPIFLLHHA
- Conjugate: PE
Compare

PE-B*54:01/Human TYR (DPIFLLHHA) MHC Tetramer (MHC-LC2466)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPIFLLHHA
- Conjugate: PE
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (KIH) (VS-0622-YF5878) (VS-0622-YF5878)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
Compare

PE-A*11:01/Human TYR (SIFEQWLRR) MHC Tetramer (MHC-LC3025)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SIFEQWLRR
- Conjugate: PE
Compare

PE-A*02:01/Human TYR (WLLGAAMVGA) MHC Tetramer (MHC-LC2939)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: WLLGAAMVGA
- Conjugate: PE
Compare

PE-B*07:02/Human TYR (IPLYRNGDF) MHC Tetramer (MHC-LC2482)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: IPLYRNGDF
- Conjugate: PE
Compare

Human Anti-Tyrosinase Recombinant Soluble TCR (clone TA4) (scTCR-1209YC-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

PE-Mamu-A1*011:01/Human TYR (SEIWRDIDF) MHC Tetramer (MHC-LC3000)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SEIWRDIDF
- Conjugate: PE
Compare

PE-B*07:02/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2513)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
Compare

Recombinant Anti-Tyr Antibody (MOB-1019)
- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, IP, FuncS
Compare

Recombinant Human Anti-Tyr Antibody (MHH-1019)
- Derivation: Human
- Type: IgG
- Application: RIA, IF, FuncS
Compare

PE-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1293)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: PE
Compare

APC-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1294)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: APC
Compare

FITC-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1295)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: FITC
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (TA4) (C-Cys) (VS-0622-YF5206)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (TD6) (C-Cys) (VS-0622-YF5207)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Recombinant Human Anti-Tyrosinase Soluble TCR (UG6) (C-Cys) (VS-0622-YF5208)
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

Human Anti-Tyrosinase Recombinant Soluble TCR (clone TD6) (scTCR-1210YC-S(P))
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*02:01
Compare

PE-A*03:01/Human TYR (YMVPFIPLYR) MHC Tetramer (MHC-LC3031)
- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMVPFIPLYR
- Conjugate: PE
Compare

Recombinant Human Anti-Tyr Antibody Fab Fragment (MHH-1019-F(E))
- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
Compare

Recombinant Human Anti-Tyr Antibody scFv Fragment (MHH-1019-S(P))
- Derivation: Human
- Type: scFv
- Application: WB, Neut, FuncS
Compare

Recombinant Anti-Tyr Antibody Fab Fragment (MOB-1019-F(E))
- Derivation: Mouse
- Type: Fab
- Application: RIA, WB, FuncS
Compare

Recombinant Anti-Tyr Antibody scFv Fragment (MOB-1019-S(P))
- Derivation: Mouse
- Type: scFv
- Application: ELISA, IF, FuncS
Compare

Anti-TYR Immunohistochemistry Kit (VS-0525-XY7664)
- Species Reactivity: Human
- Target: TYR
- Application: IHC
Compare

DrugMonitor™ Anti-Tyrosinase Antibody (VS-1224-YC1254) (VS-1224-YC1254)
- Specificity: Tyrosinase
- Type: Mouse IgG
- Application: ELISA, PK/PD, ADA control
Compare

Rabbit Anti-TYR Recombinant Antibody (clone DS3734AB) (MOR-3734)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB, ICC, IF
Compare

Anti-Mouse TYR Immunohistochemistry Kit (VS-0525-XY7665)
- Species Reactivity: Human, Mouse
- Target: TYR
- Application: IHC
Compare

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For Research Use Only. Not For Clinical Use.

Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

Tyrosinase is a multi-copper-containing, multifunctional metalloenzyme with four possible oxidation states, responsible for producing melanin pigment.

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