Ferroptosis / Oxytosis Antibody Panel (4-Hydroxynonenal, GPX4, SLC7A11)
CAT#: VS-0725-YC21
The Ferroptosis / Oxytosis Antibody Panel are sets of 3 antibodies, precisely chosen for the simultaneous detection of key markers associated with these oxidative stress-driven processes. Researchers will find antibodies against 4-Hydroxynonenal, GPX4, and SLC7A11 included in this insightful set. This panel offers a powerful and streamlined tool for investigating cellular susceptibility to oxidative damage and potential therapeutic interventions, ensuring reliable and reproducible results for your innovative studies.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| FAMAB-0367JF | Mouse Anti-GPx4 Recombinant Antibody (clone 63-1) | 63-1 | Mouse IgG2b, κ | GPx4 | Human | WB, IHC, IF | |
| VS3-FY1351 | Recombinant Rabbit Anti-SLC7A11 Antibody (clone R08-2C5) | R08-2C5 | Rabbit IgG | SLC7A11 | Human, Mouse | Western Blot, Immunoprecipitation | |
| VS-0725-YC141 | Mouse Anti-4-Hydroxynonenal Recombinant Antibody | Mouse IgG | 4-Hydroxynonenal | ELISA, ICC, IF, IHC, WB |
More Infomation
Specifications
- Targets
- 4-Hydroxynonenal, GPX4, SLC7A11
- Species Reactivity
- Human
- Research Area
- Ferroptosis and Oxytosis
- Introduction
- Ferroptosis is an iron-dependent form of regulated cell death (RCD) characterized by the accumulation of lipid hydroperoxides to lethal levels, ultimately leading to membrane rupture and cell demise. Unlike apoptosis, necroptosis, or pyroptosis, ferroptosis exhibits distinct morphological features, including reduced mitochondrial volume, increased mitochondrial membrane density, and a lack of nuclear condensation. Its unique biochemical signature revolves around iron metabolism and lipid peroxidation.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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