FITC-DRB1*04:01/Human gp100 (IYRRRLMKQDFSVPQLPHS) MHC Tetramer
CAT#: MHC-YF1310
This product is a MHC tetramer of biotinylated peptide/MHC complex composed gp100-derived peptide of IYRRRLMKQDFSVPQLPHS sequence covering 615-633 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- gp100
- Antigen Species
- Human
- Peptide
- IYRRRLMKQDFSVPQLPHS
- Range
- 615-633
- Conjugate
- FITC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Alternative Names
- P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E
- Gene ID
- 6490
- UniProt ID
- P40967
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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