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gp100

Anti-gp100 Products
- PE-Mamu-A*08/SIV gp100 (KPCVKLTP) MHC Tetramer (MHC-CN0757)
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- Class: Class I
- Antigen: gp100
- Antigen Species: SIV
- Peptide: KPCVKLTP
- Conjugate: PE
- APC-Mamu-A*08/SIV gp100 (KPCVKLTP) MHC Tetramer (MHC-CN0758)
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- Class: Class I
- Antigen: gp100
- Antigen Species: SIV
- Peptide: KPCVKLTP
- Conjugate: APC
- FITC-Mamu-A*08/SIV gp100 (KPCVKLTP) MHC Tetramer (MHC-CN0759)
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- Class: Class I
- Antigen: gp100
- Antigen Species: SIV
- Peptide: KPCVKLTP
- Conjugate: FITC
- Mamu-A*08/SIV gp100 (KPCVKLTP) MHC Tetramer (MHC-CN0760)
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- Class: Class I
- Antigen: gp100
- Antigen Species: SIV
- Peptide: KPCVKLTP
- Conjugate: Unconjugated
- Human Anti-gp100 Recombinant Soluble TCR (clone (296/107)-1) (scTCR-0490YC-S(P))
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- Epitope: YLEPGPVTL
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (296/107)-2) (scTCR-0491YC-S(P))
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- Epitope: YLEPGPVTV
- MHC: HLA-A*02:01
- Recombinant Human Anti-gp100 Soluble TCR (clone 296/107) (KIH) (VS-0622-YF7207)
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- Epitope: YLEPGPVTL
- MHC: HLA-A*02:01
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: APC
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: PE
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: FITC
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: BV421
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- Epitope: YLEPGPVTL
- MHC: HLA-A*02:01
- Recombinant Human Anti-gp100 Soluble TCR (clone 296/107) (C-Cys) (VS-0622-YF4499)
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- Epitope: YLEPGPVTL
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-2) (scTCR-0498YC-S(P))
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- Epitope: YLEAGPVTA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-3) (scTCR-0499YC-S(P))
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- Epitope: YLEPGAVTA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-4) (scTCR-0500YC-S(P))
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- Epitope: YLEPGPATA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-5) (scTCR-0501YC-S(P))
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- Epitope: YLEPGPVAA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-7) (scTCR-0502YC-S(P))
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- Epitope: YLEPGPVTV
- MHC: HLA-A*02:01
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Human Anti-gp100 Recombinant Soluble TCR (clone (gp100)-1) (scTCR-0492YC-S(P))
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- Epitope: ALEPGPVTA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (gp100)-2) (scTCR-0493YC-S(P))
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- Epitope: YLEAGPVTA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (gp100)-3) (scTCR-0494YC-S(P))
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- Epitope: YLEPGPATA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (gp100)-4) (scTCR-0495YC-S(P))
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- Epitope: YLEPGPVAA
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (gp100)-6) (scTCR-0496YC-S(P))
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- Epitope: YLEPGPVTV
- MHC: HLA-A*02:01
- Human Anti-gp100 Recombinant Soluble TCR (clone (PMEL17)-1) (scTCR-0497YC-S(P))
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- Epitope: ALEPGPVTA
- MHC: HLA-A*02:01
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.