PE-H-2Kb/HPV16 E6 (EVYDFAFRDL) MHC Tetramer
CAT#: MHC-CN0857
Specifications
- Allele
- H-2Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- HPV16 E6
- Antigen Species
- HPV
- Peptide
- EVYDFAFRDL
- Conjugate
- PE
- Application
- FCM, IHC
Target
- Antigen Introduction
- Papillomaviridae is an ancient taxonomic family of non-enveloped DNA viruses, collectively known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other amniotes such as birds, snakes and turtles. Infection by most papillomavirus types, depending on the type, is either asymptomatic (e.g. most Beta-PVs) or causes small benign tumors, known as papillomas or warts (e.g. human papillomavirus1, HPV6 or HPV11). Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous.
- Alternative Names
- HPV16 E6; Human papillomavirus type 16 E6
- Gene ID
- 1489078
- UniProt ID
- P03126
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Effective HPV16 E6 Detection
This PE-labeled tetramer worked well for detecting mouse CD8 T cells specific to the HPV16 E6 peptide EVYDFAFRDL. It was a valuable tool for our research on papillomavirus-induced immune responses.
Reliable H-2Kb Reagent
We successfully utilized this product to analyze T cells targeting the HPV16 E6 protein. The staining was clear and consistent, allowing us to accurately determine the presence of antigen-specific cells in our flow cytometry assays.
Q&As
-
Which HPV protein is targeted by this tetramer?
A: This tetramer targets the HPV16 E6 protein. It is loaded with the peptide sequence EVYDFAFRDL and is presented by the mouse H-2Kb MHC Class I molecule.
-
What is the primary application for this product?
A: The primary application for this PE-labeled tetramer is flow cytometry (FCM). It allows for the identification and analysis of mouse CD8 T cells specific for the HPV16 E6 antigen.
View the frequently asked questions answered by Creative Biolabs Support.
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "HPV16 E6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-547LC | Anti-HPV16 E6 Recombinant Antibody (1B2.27) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-548LC | Anti-HPV16 E6 Recombinant Antibody (7F10.3) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-549LC | Anti-HPV16 E6 Recombinant Antibody (4E9.7) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-550LC | Anti-HPV16 E6 Recombinant Antibody (4E10.2) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-551LC | Anti-HPV16 E6 Recombinant Antibody (6H5.3) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1876CQ | Recombinant Mouse Anti-HPV-16 E6 Antibody (2E3) | IF, IHC-P | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC257 | PE-A*03:01/HPV16 E6 (KLCLRFLSK) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC258 | APC-A*03:01/HPV16 E6 (KLCLRFLSK) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC259 | BV421-A*03:01/HPV16 E6 (KLCLRFLSK) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC434 | PE-A*02:01/HPV16 E6 (KLPQLCTEL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC435 | APC-A*02:01/HPV16 E6 (KLPQLCTEL) MHC Tetramer | FCM |
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