H-2Kb/Mouse mTERT (VGRNFTNL) MHC Monomer (CAT#: MHC-YF144)
This product is a MHC monomer of biotinylated peptide/MHC complex composed mTERT-derived peptide of VGRNFTNL sequence covering 198-205 and H-2Kb molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line LHCN-M2
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows no positivity in hepatocytes and bile duct cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_9_4_selected.jpg
(Immunohistochemical staining of human liver shows no positivity in hepatocytes and bile duct cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_9_4_selected.jpg
Figure 3 Kidney
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_7_5.jpg
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_7_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166, HBEC3-KT, hTEC/SVTERT24-B, LHCN-M2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164362-TERT/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164362-TERT/subcellular
Specifications
- Allele
- H-2Kb
- Class
- Class I
- Antigen
- mTERT
- Antigen Species
- Mouse
- Peptide
- VGRNFTNL
- Range
- 198-205
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
- Alternative Names
- TR; TP2; TRT; EST2; TCS1
- Gene ID
- 21752
- UniProt ID
- Q9JLM1
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TERT"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962 | Recombinant Anti-human TERT Antibody | WB, IHC, FuncS | IgG |
| MHH-962 | Recombinant Human Anti-human TERT Antibody | WB, Neut, FuncS | IgG |
| MRO-1480-CN | Rabbit Anti-TERT Recombinant Antibody (clone JF0586) | WB, FC | Rabbit IgG |
| ZG-0591U | Rabbit Anti-TERT Recombinant Antibody (clone 5C11) | ELISA, IHC | Rabbit IgG |
| VS3-XY1495 | Mouse Anti-TERT Recombinant Antibody (clone 7E4B8) | ELISA, WB, IHC, FC | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962-F(E) | Recombinant Anti-human TERT Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-962-F(E) | Recombinant Human Anti-human TERT Antibody Fab Fragment | WB, IHC, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962-S(P) | Recombinant Anti-human TERT Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-962-S(P) | Recombinant Human Anti-human TERT Antibody scFv Fragment | WB, Neut, FuncS | scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-050 | Recombinant Anti-human TERT VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B046(A) | Recombinant Anti-human TERT Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B046(G) | Recombinant Anti-human TERT Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
| IAB-B046(T) | Recombinant Anti-human TERT Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0581MZ | Chicken Anti-TERT Polyclonal IgY | WB | Chicken antibody |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3533 | Rabbit Anti-TERT Recombinant Antibody (clone DS3533AB) | FC, ICC, IF, IHC-Fr, IHC-P, IP, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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