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    Human Anti-GLB1 scFv-Fc Chimera (VS-0325-FY95) (CAT#: VS-0325-FY95)

    The anti-β-galactosidase scFv-Fc antibody is a recombinant antibody designed to target β-galactosidase, an enzyme commonly used as a reporter gene in molecular biology and biochemistry. The single-chain variable fragment (scFv) fused to the Fc region of an immunoglobulin allows for enhanced stability, solubility, and effective effector functions, making it a valuable tool for various applications in research and therapeutic settings.

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    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40610/814_D2_1_selected.jpg
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in leydig cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8382/ihc_selected.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40610/759_D2_1_blue_red_green.jpg
    Figure 4 IF staining of human cell line U-251 MG
    Figure 4 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40610/755_D2_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Thyroid gland
    Figure 5 Thyroid gland
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69503/154814_B_1_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Glandular cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69503/154814_A_7_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Cholangiocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69503/154814_A_9_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in tubules
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69503/154814_A_9_5.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (BEWO)
    Figure 9 RNA cell line category: Cell line enhanced (BEWO)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000170266-GLB1

    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1, scFv-Fc
    • Specificity
    • AMEF strain GLB1
    • Species Reactivity
    • AMEF strain
    • Applications
    • Immunoassay

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Target

    • Alternative Names
    • Galactosidase Beta 1; Elastin Receptor 1, 67kDa; Acid Beta-Galactosidase; EC 3.2.1.23; Lactase; ELNR1; Elastin Receptor 1 (67kD)
    • Long Name
    • Galactosidase Beta 1
    • Sequence Similarities
    • Belongs to the glycosyl hydrolase 35 family.
    • Cellular Localization
    • Lysosome
    • Post Translation Modifications
    • Glycosylation at Asn26, Asn247, Asn464, Asn498, Asn542, Asn545, and Asn555
      Modification sites at PhosphoSitePlus
      Glycosylation from GlyConnect BGAL_HUMAN (1036)
      Glycosylation from GlyGen 8 sites, 81 N-linked glycans (4 sites), 1 O-linked glycan (1 site)
    • Function
    • AMEF strain GLB1 refers to a particular strain of Acanthamoeba, which is a free-living amoeba. Specific characteristics of the GLB1 strain, often including its pathogenic potential and genetic makeup, are important in understanding Acanthamoeba infections.

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "GLB1"

    Select a product category from the dropdown menu below to view related products.
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    Fab Antibody Products IgG Antibody Products ScFv Antibody Products Rabbit Monoclonal Antibody Products Non-Human Primate (NHP) Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    DrMAB-75 Mouse Anti-GLB1 Recombinant Antibody (clone 13R4); Fab Fragment WB, FC Mouse Fab
    PFBL-361 Recombinant Mouse Anti-β-galactosidase Antibody Fab Fragment (13R4) WB, ELISA, FuncS Fab

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