Human Anti-HLA-A2 scFv-Fc Chimera (VS-0325-FY11)
CAT#: VS-0325-FY11
Anti-HLA-A2 scFv-Fc is a recombinant antibody that combines the antigen-binding capabilities of a single-chain variable fragment (scFv) with the effector functions of an immunoglobulin's fragment crystallizable (Fc) region. Anti-HLA-A2 scFv-Fc can be used to study the therapeutic potential of regulatory T cells (Tregs) in transplantation models. The scFv-Fc antibody targets the HLA-A2 molecule displaying the WT1126 peptide on leukemia cells, promoting antibody-dependent cell-mediated cytotoxicity (ADCC) through the activation of NK-92-MI cells.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human HLA-A2
- Species Reactivity
- Human
- Applications
- ELISA, ADCC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- MHC Class I, A cell surface antigen; HLA-A2
- Long Name
- MHC Class I, A cell surface antigen
- Function
- HLA-A*02 is one particular class I major histocompatibility complex (MHC) allele group at the HLA-A locus. The A*02 allele group can code for many proteins; as of December 2013 there are 456 different HLA-A*02 proteins. Serotyping can identify as far as HLA-A*02, which is typically enough to prevent transplant rejection (the original motivation for HLA identification). Genes can further be separated by genetic sequencing and analysis. HLAs can be identified with as many as nine numbers and a letter (ex. HLA-A*02:101:01:02N). HLA-A*02 is globally common, but particular variants of the allele can be separated by geographic prominence.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0325-FY11. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "HLA-A2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-13 | Recombinant Anti-human A*02 Antibody | WB, IHC, FuncS | IgG |
| MHH-13 | Recombinant Human Anti-human A*02 Antibody | IF, FC, FuncS | IgG |
| FAMAB-0167YC | Mouse Anti-HLA-A2 Recombinant Antibody (clone G1) | ELISA, FC, IHC, Cyt | Mouse IgG |
| FAMAB-0156JF | Human Anti-HLA-A2 Recombinant Antibody (clone 3PB2) | WB, ELISA, IHC, FuncS | Human IgG |
| FAMAB-0157JF | Human Anti-HLA-A2 Recombinant Antibody (clone 3PC4) | WB, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-13-F(E) | Recombinant Anti-human A*02 Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| MHH-13-F(E) | Recombinant Human Anti-human A*02 Antibody Fab Fragment | WB, ELISA, IHC, FuncS | Fab |
| FAMAB-0156JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PB2); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
| FAMAB-0157JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PC4); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
| FAMAB-0158JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PF12); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-13-S(P) | Recombinant Anti-human A*02 Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| MHH-13-S(P) | Recombinant Human Anti-human A*02 Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| FAMAB-0167-YC-S(P) | Mouse Anti-HLA-A2 Recombinant Antibody (clone G1); scFv Fragment | ELISA, FC, IHC, Cyt | Mouse scFv |
| FAMAB-0156JF-S(P) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PB2); scFv Fragment | IF, WB, ELISA, FuncS | Human scFv |
| FAMAB-0157JF-S(P) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PC4); scFv Fragment | IF, WB, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0837 | PE-A*02:01/Human HLAA2 (YAYDGKDYIA) MHC Tetramer | FCM, IHC | |
| MHC-CN0838 | APC-A*02:01/Human HLAA2 (YAYDGKDYIA) MHC Tetramer | FCM, IHC | |
| MHC-CN0839 | FITC-A*02:01/Human HLAA2 (YAYDGKDYIA) MHC Tetramer | FCM, IHC | |
| MHC-CN0840 | A*02:01/Human HLAA2 (YAYDGKDYIA) MHC Tetramer | FCM, IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, WB, BLI, SPR
Application: WB, ELISA, FuncS
-3.png)
Application: ELISA, FC, Block, SPR
-3.jpg)
Application: WB, ELISA, Neut, FuncS
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
