Mouse Anti-HLA-A2 Recombinant Antibody (clone G1); scFv Fragment (CAT#: FAMAB-0167-YC-S(P))
A recombinant Ab that exhibits a characteristic TCR-like binding specificity, yet, unlike TCRs, it did so with a high affinity in the nanomolar range. The TCR-like Ab can recognize the native MHC-peptide complex expressed on the surface of APCs, and on peptide-pulsed or native melanoma cells. Moreover, when fused to a very potent cytotoxic effector molecule in the form of a truncated bacterial toxin, it was able to specifically kill APCs in a peptide-dependent manner.
Specific Inquiry
Specifications
- Immunogen
- A single-chain HLA-A2, complexed with a common antigenic T cell HLA-A2-restricted epitope derived from the melanoma differentiation Ag gp100.
- Host Species
- Mouse
- Derivation
- Phage display library
- Type
- Mouse scFv
- Specificity
- Human HLA-A2
- Species Reactivity
- Human
- Clone
- G1
- Applications
- ELISA, FC, IHC, Cyt
- Related Disease
- Melanoma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HLA-A; Major histocompatibility complex, class I, A; HLAA
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-13-F(E) | Recombinant Anti-human A*02 Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| FAMAB-0167-YC-F(E) | Mouse Anti-HLA-A2 Recombinant Antibody (clone G1); Fab Fragment | ELISA, FC, IHC, Cyt | Mouse Fab |
| FAMAB-0156JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PB2); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
| FAMAB-0157JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PC4); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
| FAMAB-0158JF-F(E) | Human Anti-HLA-A2 Recombinant Antibody (clone 3PF12); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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