1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Human Anti-IGSF8 scFv-Fc Chimera (VS-0325-FY21) (CAT#: VS-0325-FY21)

    The anti-IGSF8 scFv-Fc antibody targets IGSF8, a member of the immunoglobulin superfamily involved in cell adhesion and signaling. It has potential therapeutic applications in diseases associated with IGSF8 dysregulation, such as certain cancers and inflammatory disorders. The scFv-Fc format enhances its stability and bioavailability, making it suitable for therapeutic use.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line SH-SY5Y
    Figure 1 IF staining of human cell line SH-SY5Y
    (Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11917/1680_E3_6_selected.jpg
    Figure 2 IF staining of human cell line HaCaT
    Figure 2 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/1802_H1_5_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human cerebellum
    Figure 3 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong positivity in neuronal processes.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11917/29657_B_8_8_selected.jpg
    Figure 4 IHC staining of human spleen
    Figure 4 IHC staining of human spleen
    (Immunohistochemical staining of human spleen shows strong nuclear and cytoplasmic positivity in cells in red pulp.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/169279_B_7_4_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/169279_B_8_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/169279_A_9_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/169279_A_7_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75970/169279_A_4_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (SK-MEL-30)
    Figure 9 RNA cell line category: Cell line enhanced (SK-MEL-30)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162729-IGSF8

    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1, scFv-Fc
    • Specificity
    • Human IGSF8
    • Species Reactivity
    • Human
    • Applications
    • ELISA
    • Related Disease
    • Cancer and inflammatory disorder

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Target

    • Alternative Names
    • Immunoglobulin Superfamily Member 8
    • Long Name
    • Immunoglobulin Superfamily Member 8
    • Cellular Localization
    • Cell membrane
    • Post Translation Modifications
    • Glycosylation at Asn50, Asn327, and Asn463
      Ubiquitination at Lys143
      Modification sites at PhosphoSitePlus
      Glycosylation from GlyConnect IGSF8_HUMAN (1394)
      Glycosylation from GlyGen 4 sites, 35 N-linked glycans (3 sites), 1 O-linked glycan (1 site)
    • Function
    • Member of the immunoglobulin superfamily (IgSF) that links tetraspanin-enriched microdomains to the actin cytoskeleton and plays several important roles in innate and adaptive immunity (PubMed:11504738, 14662754).
      Acts as an inducible receptor of HSPA8 on dendritic cells to enhance the CCL21/SLC-dependent migration of activated mature dendritic cells while attenuating their antigen-specific stimulatory capacities.

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "IGSF8"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibodies Fab Antibodies ScFv Antibodies Rabbit Monoclonal Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    MOB-3451z Mouse Anti-IGSF8 Recombinant Antibody (MOB-3451z) ELISA Mouse IgG1, κ
    CBPAB-050LC Rabbit Anti-IGSF8 Polyclonal Antibody IHC, WB, IF Rabbit IgG

    Customer Reviews and Q&As

    Submit a review or a question

    There are currently no Customer reviews or questions for VS-0325-FY21. Click the button above to contact us or submit your feedback about this product.

    Popular products with customers

    Figure 1 Recombinant Anti-5-FU Antibody (MOB-12) in ELISA

    Recombinant Anti-5-FU Antibody (CAT# MOB-12)
    Application: WB, Neut, FuncS

    Figure 2 Anti-Human CSF1R Antibody (TAB-H23) in ELISA

    Anti-Human CSF1R Recombinant Antibody (TAB-H23) (CAT# TAB-H23)
    Application: WB, ELISA, IP, FC, FuncS, Neut, IF

    Figure 3 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in ELISA

    Anti-Human NRP1 Recombinant Antibody (Vesencumab) (CAT# TAB-264)
    Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

    Figure 2 Anti-Human Nogo-A Recombinant Antibody (TAB-903) in HPLC

    Anti-Human Nogo-A Recombinant Antibody (TAB-903) (CAT# TAB-903)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 4 Anti-Human CSF2 Recombinant Antibody (TAB-H44) in SEC-HPLC

    Anti-Human CSF2 Recombinant Antibody (TAB-H44) (CAT# TAB-H44)
    Application: Neut, ELISA, IF, IP, FuncS, FC, IHC

    Figure 9 Anti-Human BAFF Recombinant Antibody in ELISA

    Anti-Human BAFF Recombinant Antibody (TAB-216) (CAT# TAB-216)
    Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

    Figure 2 Anti-alpha 4 beta 7 Antibody (TAB-H75) in Dot Blot

    Anti-Human ITGA4+ITGB7 Recombinant Antibody (TAB-H75) (CAT# TAB-H75)
    Application: FC, IP, ELISA, Neut, FuncS, IF, WB

    Figure 2 Chimeric (mouse/Human) Anti-TNFRSF8 Recombinant Antibody (TAB-153) in ELISA

    Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (TAB-153) (CAT# TAB-153)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 2 Recombinant Anti-VEEV E2 Antibody (PABL-742) in HPLC

    Recombinant Human Anti-VEEV E2 Antibody (3B4C-4) (CAT# PABL-742)
    Application: Neut

    Figure 2 Human TIM3 Recombinant Antibody (TAB-0366CL) in WB

    Anti-Human TIM3 Recombinant Antibody (TSR-022) (CAT# TAB-0366CL)
    Application: FC, FuncS

    Figure 3 Anti-FCRN Antibody in Dot Blot.

    Human Anti-FCRN Recombinant Antibody; Fab Fragment (TAB-0145CL-F(E)) (CAT# TAB-0145CL-F(E))
    Application: ELISA, FC, Block, SPR

    Figure 1 Anti-BNP Antibody (PABX-017) in ELISA

    Recombinant Mouse Anti-BNP Antibody (106.3) (CAT# PABX-017)
    Application: FuncS

    Figure 3 Anti-CD276 Antibody (TAB-424CQ) in DB

    Anti-Human CD276 Recombinant Antibody (TAB-424CQ) (CAT# TAB-424CQ)
    Application: ELISA, IHC, FC, IP, IF, FuncS

    Figure 2 Recombinant Anti-FGFR3 Antibody (PRO-001) (HPAB-0160-YC) in ELISA

    Human Anti-FGFR3 Recombinant Antibody (clone PRO-001) (CAT# HPAB-0160-YC)
    Application: FC, FuncS

    Figure 1 Mouse Anti-ROR1 Recombinant Antibody (HPAB-0308-CN) in SDS-PAGE

    Mouse Anti-ROR1 Recombinant Antibody (HPAB-0308-CN) (CAT# HPAB-0308-CN)
    Application: ELISA, FC

    Figure 3 Human Anti-HIV-1 gp160 Recombinant Antibody (MRO-3786CQ) in ELISA

    Human Anti-HIV-1 gp160 Recombinant Antibody (MRO-3786CQ) (CAT# MRO-3786CQ)
    Application: FuncS

    Figure 2 Recombinant Mouse Anti-CD22 Antibody (HPAB-N0324-YC) in HPLC

    Mouse Anti-CD22 Recombinant Antibody (HPAB-N0324-YC) (CAT# HPAB-N0324-YC)
    Application: FuncS

    Figure 2 Human Anti-HLA-DR4 Recombinant Antibody (HPAB-0826-FY) in HPLC

    Human Anti-HLA-DR4/GAD-555-567 Recombinant Antibody (clone G3H8) (CAT# HPAB-0826-FY)
    Application: FC

    Figure 2 Human Anti-Insulin Recombinant Antibody (clone mAb48) (FAMAB-0224WJ) in ELISA

    Human Anti-Insulin Recombinant Antibody (clone mAb48) (CAT# FAMAB-0224WJ)
    Application: ELISA, WB

    Figure 4 Human Anti-Rotavirus VP8* Recombinant Antibody (clone mAb9) (PABJ-0170) in DB

    Human Anti-Rotavirus VP8* Recombinant Antibody (clone mAb9) (CAT# PABJ-0170)
    Application: ELISA, Neut

    For Research Use Only. Not For Clinical Use.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare