Recombinant Human Anti-NSDHL Soluble TCR (BD12) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2043)
Human TCR (BD12) recognizes NSDHL peptide (ILTGLNYEA) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (BD12). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum & lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/248/24_C1_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum & lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/248/24_C1_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to endoplasmic reticulum & lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/25_C4_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to endoplasmic reticulum & lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/25_C4_1_selected.jpg
Figure 3 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_4_6.jpg
Figure 4 Epididymis
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_3_6.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_3_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/571/1851_A_8_8.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147383-NSDHL
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147383-NSDHL
Specifications
- Host Species
- Human
- Target
- NSDHL
- Species Reactivity
- Human
- Epitope
- ILTGLNYEA
- MHC
- HLA-A2
- Clone
- BD12
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- CHILD syndrome
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- NAD(P) Dependent Steroid Dehydrogenase-Like; Short Chain Dehydrogenase/Reductase Family 31E, Member 1; Protein H105e3; EC 1.1.1.170; H105E3; Sterol-4-Alpha-Carboxylate 3-Dehydrogenase, Decarboxylating; SDR31E1; XAP104
- Gene ID
- 50814
- UniProt ID
- Q15738
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1463CT | Recombinant Mouse anti-Human NSDHL Monoclonal antibody (EML145) | WB | |
| VS4-CJ60 | Recombinant Rabbit Anti-NSDHL Antibody (clone 20F2) | ELISA, WB, IHC | Rabbit IgG |
| VS3-FY2053 | Rabbit Anti-NSDHL Recombinant Antibody (clone R04-6I5) | WB, IP | Rabbit IgG |
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