Recombinant Human Anti-RYR3 Soluble TCR (AB10) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2328)
Human TCR (AB10) recognizes RYR3 peptide (VLNYFEPYL) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (AB10). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62004/1505_F8_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62004/1505_F8_2_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (A549, RH-30, RPTEC TERT1, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198838-RYR3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198838-RYR3
Specifications
- Host Species
- Human
- Target
- RYR3
- Species Reactivity
- Human
- Epitope
- VLNYFEPYL
- MHC
- HLA-A2
- Clone
- AB10
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Ryanodine Receptor 3; Brain Ryanodine Receptor-Calcium Release Channel; Brain-Type Ryanodine Receptor; Type 3 Ryanodine Receptor; RYR-3; HBRR; RyR3
- Gene ID
- 6263
- UniProt ID
- Q15413
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