Recombinant Human Anti-TERT Soluble TCR (ILA1α1β2) (C-Cys)

Name: Recombinant Human Anti-TERT Soluble TCR (ILA1α1β2) (C-Cys)
SKU: VS-0622-YF5171
Rating: 5 (1 reviews)

CAT#: VS-0622-YF5171

Human TCR (ILA1α1β2) recognizes TERT peptide (ILAKFLHWL) in the context of HLA-A*02:01. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line LHCN-M2

Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human liver

Immunohistochemical staining of human liver shows no positivity in hepatocytes and bile duct cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_9_4_selected.jpg

Normal Tissue Figure 3 Kidney

Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_7_5.jpg

RNA Expression Figure 4 RNA cell line category: Cell line enhanced.

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164362-TERT/subcellular

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Specifications

Host Species
Human

Target
TERT

Species Reactivity
Human

Epitope
ILAKFLHWL

MHC
HLA-A*02:01

Clone
ILA1α1β2

Type
Soluble TCR (C-Cys)

TCR Expression Strategy
C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.

Target

Alternative Names
Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; Telomerase Catalytic Subunit; EC 2.7.7.49; HEST2; TCS1; EST2; TP2

Gene ID
7015

UniProt ID
O14746

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Datasheet

Datasheet - VS-0622-YF5171.pdf

MSDS

MSDS - VS-0622-YF5171.pdf

COA

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