Recombinant Mouse Anti-Rrm1 Soluble TCR (B6.2.16) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2325)
Mouse TCR (B6.2.16) recognizes Rrm1 peptide (FQIVNPHLL) in the context of H2-Dᵇ. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (B6.2.16). Please note that the activity is not guaranteed.

(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/if_selected.jpg

(Immunohistochemical staining of human tonsil shows cytoplasmic positivity in germinal center.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/137943_A_5_8_selected.jpg

(High expression in tonsil)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_6_8_val_selected.jpg

(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_4_6.jpg

(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_8_8.jpg

(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_B_8_5.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167325-RRM1
Specifications
- Host Species
- Mouse
- Target
- Rrm1
- Species Reactivity
- Mouse
- Epitope
- FQIVNPHLL
- MHC
- H2-Dᵇ
- Clone
- B6.2.16
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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