Mouse Anti-RSV F protein scFv-Fc Chimera (VS-0425-FY177)
CAT#: VS-0425-FY177
The anti-RSV fusion glycoprotein scFv-FC is a monoclonal antibody designed to target the fusion glycoprotein of the Respiratory Syncytial Virus (RSV). The scFv-FC format combines a single-chain variable fragment (scFv) that specifically binds to the RSV fusion glycoprotein with the human Fc domain, enhancing its stability, half-life, and potential for therapeutic applications. This antibody can be used for research, diagnostic, and therapeutic purposes, particularly in the field of virology and infectious diseases.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Rabies virus (RABV) fusion glycoprotein
- Species Reactivity
- Rabies virus (RABV)
- Applications
- Western Blot, ELISA, Inhibition
- Related Disease
- Rabies virus (RABV)
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- RSV fusion glycoprotein; RSV F protein
- Long Name
- RSV fusion glycoprotein
- Function
- The Respiratory Syncytial Virus (RSV) Fusion (F) protein is a crucial transmembrane glycoprotein located on the viral envelope. Its primary function is to mediate the fusion of the viral membrane with the host cell membrane, a necessary step for viral entry and infection.
The F protein undergoes a significant conformational change during this process, transitioning from a metastable prefusion state to a more stable postfusion state. This refolding exposes a hydrophobic fusion peptide that inserts into the host cell membrane, bringing the viral and cellular membranes into close proximity to facilitate fusion and the release of the viral genome into the cell.
Furthermore, the RSV F protein is a major target for neutralizing antibodies produced during natural infection or elicited by vaccines. Antibodies that can block the F protein's conformational change and fusion activity are key to preventing RSV infection and disease. Due to its essential role in viral entry and its immunogenicity, the F protein is a primary focus for the development of RSV vaccines and antiviral therapies.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| MOB-864-F(E) | Recombinant Anti-RSV fusion (F) protein Antibody Fab Fragment | IF, WB, FuncS | Fab |
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| CAT | Product Name | Application | Type |
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| MOB-864-S(P) | Recombinant Anti-RSV fusion (F) protein Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
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