PE-Human CD1d Tetramer - α-GalCer
CAT#: MHC-YF787
This product is a tetramer of CD1d tetramer loaded with α-GalCer and fluorescent-labeled with PE. It can be used to identify human natural killer (NK) T cells by flow cytometry and the frequency of antigen-specific NKT cells.
Specifications
- Allele
- CD1d
- Class
- Non-classical MHC
- MHC Species
- Human
- Antigen
- Alpha-galactosylceramide (alpha-GalCer)
- Antigen Species
- Human
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- α-GalCer is a synthetic glycolipid which is a potent activator of iNKT cells, and a model CD1d antigen.
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Effective NK Cell Identification
This PE-labeled tetramer was very effective for identifying human natural killer T cells in my flow cytometry experiments. The fluorescence signal was bright and distinct, allowing for a clear separation of the cell populations I was interested in studying.
Reliable Alpha-GalCer Loading
I chose this product because it comes pre-loaded with alpha-GalCer, which is a potent activator for iNKT cells. The reagent performed consistently across multiple replicates, helping us accurately determine the frequency of antigen-specific NKT cells in our samples.
Q&As
-
What is the primary application for this PE-labeled CD1d tetramer?
A: This product is primarily designed for use in flow cytometry (FCM). It is a CD1d tetramer conjugated with PE, specifically developed to identify human natural killer (NK) T cells and determine the frequency of these antigen-specific cells in your samples.
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Is this tetramer loaded with any specific antigen?
A: Yes, this CD1d tetramer is pre-loaded with Alpha-galactosylceramide (alpha-GalCer). Alpha-GalCer is a synthetic glycolipid that serves as a model CD1d antigen and is known to be a potent activator of invariant natural killer T (iNKT) cells.
View the frequently asked questions answered by Creative Biolabs Support.
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See other products
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF790 | APC-Human CD1d Tetramer - α-GalCer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF793 | PE-Mouse CD1d Tetramer - α-GalCer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF796 | APC-Mouse CD1d Tetramer - α-GalCer | FCM |
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