PE-Mouse CD1d Tetramer - α-GalCer

CAT#: MHC-YF793

This product is a tetramer of CD1d tetramer loaded with α-GalCer and fluorescent-labeled with PE. It can be used to identify mouse natural killer (NK) T cells by flow cytometry and the frequency of antigen-specific NKT cells.

Specifications

  • Allele
  • CD1d
  • Class
  • Non-classical MHC
  • MHC Species
  • Human
  • Antigen
  • Alpha-galactosylceramide (alpha-GalCer)
  • Antigen Species
  • Mouse
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • α-GalCer is a synthetic glycolipid which is a potent activator of iNKT cells, and a model CD1d antigen.
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Breast cancer biomarkers at key points during disease progression
Identification of Mouse NKT Cells
This PE-labeled mouse CD1d tetramer was exactly what we needed to identify natural killer T cells in our mouse samples. The alpha-GalCer loading makes it a potent tool for detecting these specific cells, and the flow cytometry results were very clear.
Breast cancer biomarkers at key points during disease progression
High Quality CD1d Reagent
The staining obtained with this alpha-GalCer loaded tetramer was bright and specific. It allowed us to accurately determine the frequency of antigen-specific NKT cells in murine tissues, which was critical for our study's success.

Q&As

  1. What is the difference between this product and the human version?

    A: This product is a mouse CD1d tetramer, whereas the human version uses human CD1d. It is specifically designed to identify mouse natural killer (NK) T cells and is loaded with Alpha-galactosylceramide (alpha-GalCer).

  2. Can I use this to measure the frequency of NKT cells?

    A: Yes, this PE-labeled tetramer is intended for use in flow cytometry to identify mouse NKT cells. It allows you to determine the frequency of antigen-specific NKT cells that recognize the alpha-GalCer ligand presented by CD1d.

View the frequently asked questions answered by Creative Biolabs Support.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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