Recombinant Anti-ATP6AP2 Vesicular Antibody, EV Displayed (VS-0425-YC452)
CAT#: VS-0425-YC452
The Recombinant Anti-ATP6AP2 Vesicular Antibody, EV Displayed (VS-0425-YC452) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ATP6AP2-expressed cells or tissues. The ATP6AP2 is a protein associated with ATPases, involved in processes like acidification and pH regulation.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells and in cells of granular layer.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_8_3.jpg
Normal Tissue
Figure 4 Rectum
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_4_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_4_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3156/20177_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182220-ATP6AP2
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ATP6AP2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- ATPase H+ transporting accessory protein 2
- Molecular Function
- Receptor
- Introduction
- This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
- Alternative Names
- APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR
- Gene ID
- 10159
- UniProt ID
- O75787
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Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction
Downloadable Resources
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Datasheet
MSDS
COA
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See other products for "ATP6AP2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0319-YC | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3) | WST-1 assay, Inhib | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0320-YC | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8) | WST-1 assay, Inhib | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0319-YC-S(P) | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3); scFv Fragment | WST-1 assay, Inhib | Mouse scFv |
| HPAB-N0320-YC-S(P) | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8); scFv Fragment | WST-1 assay, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0319-YC-F(E) | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 67-3); Fab Fragment | WST-1 assay, Inhib | Mouse Fab |
| HPAB-N0320-YC-F(E) | Mouse Anti-ATP6AP2 Recombinant Antibody (clone 48-8); Fab Fragment | WST-1 assay, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY209 | Anti-ATP6AP2 Immunohistochemistry Kit | IHC |
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