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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Intracellular, Membrane (different isoforms)
Cell type enhanced (Hofbauer cells)
Low immune cell specificity
Low cell line specificity
Interacts with renin (PubMed:12045255). Accessory component of the multisubunit proton-transporting vacuolar (V)-ATPase protein pump (PubMed:33065002). Interacts (via N-terminus) with ATP6AP1 (via N-terminus) (PubMed:29127204, PubMed:33065002). Interacts with ATP6V0D1; ATP6V0D1 is a V-ATPase complex subunit and the interaction promotes V-ATPase complex assembly (PubMed:33065002, PubMed:30374053). Interacts with TMEM9; TMEM9 is a V-ATPase assembly regulator and the interaction induces the interaction with ATP6V0D1 (PubMed:30374053). Interacts with VMA21 (via N-terminus); VMA21 is a V-ATPase accessory component (PubMed:29127204).
Receptor