Recombinant Anti-BMPR1B Vesicular Antibody, EV Displayed (VS-0425-YC475)
CAT#: VS-0425-YC475
The Recombinant Anti-BMPR1B Vesicular Antibody, EV Displayed (VS-0425-YC475) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BMPR1B-expressed cells or tissues. The BMPR1B is a receptor for BMPs, involved in bone formation and associated with primary pulmonary hypertension.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, MCF7, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138696-BMPR1B
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BMPR1B
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Bone morphogenetic protein receptor type 1B
- Biological Process
- Chondrogenesis
- Molecular Function
- Kinase, Receptor, Serine/threonine-protein kinase, Transferase
- Introduction
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
- Alternative Names
- ALK6, CDw293
- Gene ID
- 658
- UniProt ID
- O00238
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Related Signaling Pathways
TGF-β Signaling Pathway
Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1501MZ | Recombinant Mouse Anti-Human BMPR1B Antibody | WB | Mouse antibody |
| MRO-1699-CN | Rabbit Anti-BMPR1B Polyclonal Antibody (MRO-1699-CN) | WB, IF, IHC | Rabbit IgG |
| HPAB-M0442-YC | Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0442-YC) | ELISA | Mouse IgG |
| HPAB-M0443-YC | Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0443-YC) | ELISA | Mouse IgG |
| HPAB-M0444-YC | Human Anti-BMPR1B Recombinant Antibody (HPAB-M0444-YC) | ELISA | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0442-YC-S(P) | Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0442-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-M0443-YC-S(P) | Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0443-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-M0444-YC-S(P) | Human Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0444-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-M0445-YC-S(P) | Human Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0445-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-M0446-YC-S(P) | Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0446-YC-S(P)) | ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0442-YC-F(E) | Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0442-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-M0443-YC-F(E) | Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0443-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-M0444-YC-F(E) | Human Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0444-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0445-YC-F(E) | Human Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0445-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0446-YC-F(E) | Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0446-YC-F(E)) | ELISA, IHC | Mouse Fab |
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