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BMPR1B

Anti-BMPR1B Products
- Recombinant Mouse Anti-Human BMPR1B Antibody (MOB-1501MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Rabbit Anti-BMPR1B Polyclonal Antibody (MRO-1699-CN) (MRO-1699-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC
- Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0442-YC) (HPAB-M0442-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0443-YC) (HPAB-M0443-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody (HPAB-M0444-YC) (HPAB-M0444-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody (HPAB-M0445-YC) (HPAB-M0445-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0446-YC) (HPAB-M0446-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IHC
- Mouse Anti-BMPR1B Recombinant Antibody (HPAB-M0447-YC) (HPAB-M0447-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IHC
- Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0442-YC-S(P)) (HPAB-M0442-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0443-YC-S(P)) (HPAB-M0443-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0444-YC-S(P)) (HPAB-M0444-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0445-YC-S(P)) (HPAB-M0445-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0446-YC-S(P)) (HPAB-M0446-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IHC
- Mouse Anti-BMPR1B Recombinant Antibody; scFv Fragment (HPAB-M0447-YC-S(P)) (HPAB-M0447-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IHC
- Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0442-YC-F(E)) (HPAB-M0442-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0443-YC-F(E)) (HPAB-M0443-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0444-YC-F(E)) (HPAB-M0444-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0445-YC-F(E)) (HPAB-M0445-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0446-YC-F(E)) (HPAB-M0446-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IHC
- Mouse Anti-BMPR1B Recombinant Antibody; Fab Fragment (HPAB-M0447-YC-F(E)) (HPAB-M0447-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IHC
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- Species Reactivity: Human
- Target: BMPR1B
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Protein class
CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Astrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A549, MCF7, SH-SY5Y)
Interaction
Interacts with high affinity with GDF5; positively regulates chondrocyte differentiation. Interacts with SCUBE3 (PubMed:33308444).
Molecular function
Kinase, Receptor, Serine/threonine-protein kinase, Transferase
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