Recombinant Anti-C3AR1 Vesicular Antibody, EV Displayed (VS-0425-YC750)

CAT#: VS-0425-YC750

The Recombinant Anti-C3AR1 Vesicular Antibody, EV Displayed (VS-0425-YC750) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to C3AR1-expressed cells or tissues. C3AR1 is a receptor for complement component C3a, triggering immune responses like chemotaxis upon C3a binding.

Gene Expression
Figure 1 Lymph node Figure 2 RNA cell line category: Cell line enriched (HMC-1)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • C3AR1
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Complement C3a receptor 1
  • Biological Process
  • Chemotaxis
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Introduction
  • C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is a G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization.
  • Alternative Names
  • AZ3B, C3AR
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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