Mouse Anti-C3AR1 Recombinant Antibody (clone 3G7) (CAT#: FAMAB-0110JF)

Recombinant mouse monoclonal antibody binds to the second extracellular loop of the human C3a receptor (C3AR1). This anti-C3AR1 antibody (3G7) can be useful in the study of the modulation of immunity, arthritis, diet-induced obesity and cancers.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
IHC

Figure 1 C3aR1, in the damaged neural parenchyma.

Figure 1 C3aR1, in the damaged neural parenchyma.

Representative images of C3aR1 staining during the acute (1 day) and more chronic (35 days) phase of SCI.

Brennan, F. H., Jogia, T., Gillespie, E. R., Blomster, L. V., Li, X. X., Nowlan, B., ... & Taylor, S. M. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI insight, 4(9).

FC

Figure 2 FACS analysis using specific antibody against C3aR1.

Figure 2 FACS analysis using specific antibody against C3aR1.

All experiments were done in triplicate and repeated at least three times.

Brennan, F. H., Jogia, T., Gillespie, E. R., Blomster, L. V., Li, X. X., Nowlan, B., ... & Taylor, S. M. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI insight, 4(9).


Specifications

  • Immunogen
  • Second extracellular loop of the C3aR
  • Host Species
  • Mouse
  • Derivation
  • Human phage display scFv library
  • Type
  • Mouse IgG
  • Specificity
  • Human C3AR1
  • Species Reactivity
  • Human
  • Clone
  • 3G7
  • Applications
  • IHC, FC
  • Related Disease
  • Arthritis, diet-induced obesity, cancers

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The C3AR1 antibody has been reported in applications of Flow Cytometry, Immunohistochemistry.

Target

  • Alternative Names
  • C3AR1; complement component 3a receptor 1; AZ3B; C3AR; HNFAG09; C3a receptor

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

Fab Fragment Antibody

scFv Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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