Recombinant Anti-CALCR Vesicular Antibody, EV Displayed (VS-0425-YC246)
CAT#: VS-0425-YC246
The Recombinant Anti-CALCR Vesicular Antibody, EV Displayed (VS-0425-YC246) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CALCR-expressed cells or tissues. The CALCR is a receptor for calcitonin, regulating bone resorption and associated with osteoporosis.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SuSa
Immunofluorescent staining of human cell line SuSa shows localization to centriolar satellites, cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/1968_E2_2_selected.jpg
Normal Tissue
Figure 2 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_6_6.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (RPTEC TERT1, SuSa, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004948-CALCR
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CALCR
- Host Animal
- Mouse
- Antibody Isotype
- IgG2a
- Species Reactivity
- Human, Rabbit
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Calcitonin receptor
- Cellular Localization
- Cell Junctions, Vesicles, Centriolar satellite
- Introduction
- This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
- Alternative Names
- CT-R, CTR
- Gene ID
- 799
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CALCR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B017(A) | Recombinant Anti-human CALCR Intrabody [(D-Arg)9] | ELISA, IF, Neut, FuncS | scFv-(D-Arg)9 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B017(G) | Recombinant Anti-human CALCR Intrabody [+36 GFP] | ELISA, Neut, FuncS | scFv-(+36GFP) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B017(T) | Recombinant Anti-human CALCR Intrabody [Tat] | PCA, WB, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1471CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1471CL) | FC, ELISA, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1472CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1472CL) | IF, FC, ELISA, IHC | Mouse IgG2A |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1473CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1473CL) | FC, ELISA, IHC | Mouse IgG2A |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1471CL-S(P) | Mouse Anti-CALCR Recombinant Antibody; scFv Fragment (TAB-1471CL-S(P)) | FC, ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1472CL-S(P) | Mouse Anti-CALCR Recombinant Antibody; scFv Fragment (TAB-1472CL-S(P)) | IF, FC, ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1473CL-S(P) | Mouse Anti-CALCR Recombinant Antibody; scFv Fragment (TAB-1473CL-S(P)) | FC, ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1951MZ | Mouse Anti-CALCR Recombinant Antibody (clone 27/00-3G2) | ELISA, IHC-P, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABS-0272 | Camelid Anti-CALCR Recombinant Antibody (clone nb35) | ELISA | Camelid VHH |
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