Recombinant Anti-CALCRL Vesicular Antibody, EV Displayed (VS-0425-YC285) (CAT#: VS-0425-YC285)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CALCRL

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Calcitonin receptor like receptor

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Plasma membrane

• Introduction
• CALCRL (Calcitonin Receptor Like Receptor) is a Protein Coding gene. Diseases associated with CALCRL include Pheochromocytoma and Migraine With Or Without Aura 1. Among its related pathways are Peptide ligand-binding receptors and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and protein transporter activity. An important paralog of this gene is CALCR.

• Alternative Names
• CGRPR, CRLR

• Gene ID
• 10203

• UniProt ID
• Q16602

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