Recombinant Anti-CCR9 Vesicular Antibody, EV Displayed (VS-0425-YC662)

CAT#: VS-0425-YC662

The Recombinant Anti-CCR9 Vesicular Antibody, EV Displayed (VS-0425-YC662) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CCR9-expressed cells or tissues. CCR9 is a chemokine receptor associated with diseases like celiac disease 1, involved in signaling pathways like Akt signaling and allograft rejection. It shares a paralog, CCR7.

Gene Expression
Figure 1 RNA cell line category: Cell line enriched (MOLT-4)

Recombinant Antibody

  • Application
  • Cyt, ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CCR9
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • C-C motif chemokine receptor 9
  • Biological Process
  • Host-virus interaction
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Cellular Localization
  • Plasma membrane, Endoplasmic reticulum
  • Introduction
  • CCR9 (C-C Motif Chemokine Receptor 9) is a Protein Coding gene. Diseases associated with CCR9 include Celiac Disease 1 and Cd45 Deficiency. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CCR7.
  • Alternative Names
  • CDw199, GPR-9-6, GPR28
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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