Recombinant Anti-CD207 Vesicular Antibody, EV Displayed (VS-0425-YC500) (CAT#: VS-0425-YC500)
The Recombinant Anti-CD207 Vesicular Antibody, EV Displayed (VS-0425-YC500) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD207-expressed cells or tissues. CD207 is associated with antigen presentation and pathways like innate immunity. CD207 is tied to conditions such as Langerhans cell histiocytosis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HAP1
(Immunofluorescent staining of human cell line HAP1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/1973_E10_5_cr5de7b118a3d6b_selected.jpg
(Immunofluorescent staining of human cell line HAP1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/1973_E10_5_cr5de7b118a3d6b_selected.jpg
Figure 2 Skin
(Langerhans
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_B_7_1.jpg
(Langerhans
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_B_7_1.jpg
Figure 3 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_A_9_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_A_9_8.jpg
Figure 4 RNA cell line category: Cell line enriched (AN3-CA)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116031-CD207
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116031-CD207
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD207
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD207 molecule
- Cellular Localization
- Cytosol
- Introduction
- CD207 (CD207 Molecule) is a Protein Coding gene. Diseases associated with CD207 include Birbeck Granule Deficiency and Langerhans Cell Histiocytosis. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and mannose binding. An important paralog of this gene is CLEC4F.
- Alternative Names
- CLEC4K, Langerin
- Gene ID
- 50489
- UniProt ID
- Q9UJ71
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-169 | Recombinant Human Anti-human CD207 Antibody | WB, FC, FuncS | IgG |
| HPAB-AP027-YC | Mouse Anti-CD207 Recombinant Antibody (HPAB-AP027-YC) | ELISA, FC | Mouse IgG |
| HPAB-AP028-YC | Mouse Anti-CD207 Recombinant Antibody (HPAB-AP028-YC) | ELISA, FC | Mouse IgG |
| VS3-FY261 | Recombinant Mouse Anti-CD207 Antibody (clone 2E1B2) | ELISA, IHC, FC, ICC | Mouse IgG1 |
| VS3-XY3294 | Rabbit Anti-CD207 Recombinant Antibody (clone R01-6X3) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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