Recombinant Anti-CD63 Vesicular Antibody, EV Displayed (VS-0425-YC180)
CAT#: VS-0425-YC180
The Recombinant Anti-CD63 Vesicular Antibody, EV Displayed (VS-0425-YC180) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD63-expressed cells or tissues. The CD63 is a protein involved in pathways responding to elevated platelet cytosolic Ca2+ and associated with conditions such as Hermansky-Pudlak Syndrome.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73506/1798_B5_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26356/if_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26356/ihc_selected.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_4_6.jpg
Normal Tissue
Figure 8 Bone marrow
Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26880_B_6_4.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (ASC diff)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000135404-CD63
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD63
- Host Animal
- Mouse
- Antibody Isotype
- IgG1 kappa
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD63 molecule
- Biological Process
- Protein transport, Transport
- Cellular Localization
- Vesicles
- Introduction
- CD63 (CD63 Molecule) is a Protein Coding gene. Diseases associated with CD63 include Hermansky-Pudlak Syndrome and Melanoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. An important paralog of this gene is TSPAN33.
- Alternative Names
- ME491, MLA1, TSPAN30
- Gene ID
- 967
- UniProt ID
- P08962
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC180. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CD63"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1956z | Mouse Anti-CD63 Recombinant Antibody (clone 38C9) | WB, ELISA, FC, ICC, IF, IP, Dot, FuncS | Mouse IgG1, κ |
| HPAB-0071-YJ | Human Anti-CD63 Recombinant Antibody (clone Hu33-11A) | FC, ELISA, IHC | Humanized IgG, κ |
| ZG-0605F | Mouse Anti-CD63 Recombinant Antibody (clone NKI/C3) | IHC-P | Mouse IgG1 |
| VS3-CJ528 | Mouse Anti-CD63 Recombinant Antibody (clone H5C6) | IF, FC | Mouse IgG1 |
| VS3-CJ529 | Mouse Anti-CD63 Recombinant Antibody (clone PT1531) | IHC-P | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0575 | Hi-Affi™ Rabbit Anti-CD63 Recombinant Antibody (clone DS575AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0071-YJ-S(P) | Human Anti-CD63 Recombinant Antibody (clone Hu33-11A); scFv Fragment | FC, ELISA, IHC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0071-YJ-F(E) | Human Anti-CD63 Recombinant Antibody (clone Hu33-11A); Fab Fragment | FC, ELISA, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY64 | CytoStream™ Mouse Anti-CD63 Recombinant Antibody (clone AD1) | FC, IHC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY369 | Anti-CD63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1207 | Anti-Mouse CD63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1208 | Anti-Rat CD63 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: FC, IHC, FuncS, Inhib, Cyt
Application: FuncS, Inhib, IP, ELISA
-2.png)
Application: WB, ELISA
Application: ELISA, IHC, FC, WB, IF, IA
Application: WB, IHC, ELISA, FC
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: Neut, FC, IHC-Fr, IP, BA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
