Recombinant Anti-CDH6 Vesicular Antibody, EV Displayed (VS-0425-YC159)
CAT#: VS-0425-YC159
The Recombinant Anti-CDH6 Vesicular Antibody, EV Displayed (VS-0425-YC159) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH6-expressed cells or tissues. The CDH6 is Cadherin 6, involved in pathways like Ectoderm Differentiation and ERK Signaling, associated with renal cell carcinoma.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7403/1907_F3_2_selected.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25274/55631_A_9_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25274/55631_A_7_5.jpg
Normal Tissue
Figure 4 Cerebral cortex
Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25274/55631_B_8_5.jpg
Normal Tissue
Figure 5 Cerebellum
Purkinje cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25274/55631_B_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (EFO-21)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113361-CDH6
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH6
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 6
- Biological Process
- Cell adhesion
- Cellular Localization
- Plasma membrane, Cell Junctions
- Introduction
- CDH6 (Cadherin 6) is a Protein Coding gene. Diseases associated with CDH6 include Renal Cell Carcinoma, Nonpapillary. Among its related pathways are Ectoderm Differentiation and ERK Signaling. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH10.
- Gene ID
- 1004
- UniProt ID
- P55285
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Datasheet
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See other products for "CDH6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-405LC | Human Anti-CDH6 Recombinant Antibody (TAB-405LC) | ELISA, FC | Human IgG |
| TAB-405LC-S(P) | Human Anti-CDH6 Recombinant Antibody; scFv Fragment (TAB-405LC-S(P)) | ELISA, FC | Human scFv |
| TAB-405LC-F(E) | Human Anti-CDH6 Recombinant Antibody; Fab Fragment (TAB-405LC-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0621 | Hi-Affi™ Rabbit Anti-CDH6 Recombinant Antibody (clone DS621AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-397 | Human Anti-CDH6 Recombinant Antibody (clone Ab-HKT288) | ELISA, FC | Human IgG1 |
| HPAB-0391-FY | Human Anti-CDH6 Recombinant Antibody (HPAB-0391-FY) | FC, ELISA, Activ | Human IgG |
| HPAB-0392-FY | Human Anti-CDH6 Recombinant Antibody (HPAB-0392-FY) | FC, ELISA, Activ | Human IgG |
| ZG-0979F | Mouse Anti-CDH6 Recombinant Antibody (clone 2B6) | ICC, IHC-Fr, IHC-P, WB | Mouse IgG1 |
| VS-0723-WK69 | Human Anti-CDH6 Recombinant Antibody (VS-0723-WK69) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-397 | Human Anti-CDH6 Recombinant Antibody (clone Ab-HKT288); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0391-FY-F(E) | Human Anti-CDH6 Recombinant Antibody; Fab Fragment (HPAB-0391-FY-F(E)) | FC, ELISA, Activ | Human Fab |
| HPAB-0392-FY-F(E) | Human Anti-CDH6 Recombinant Antibody; Fab Fragment (HPAB-0392-FY-F(E)) | FC, ELISA, Activ | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-397 | Human Anti-CDH6 Recombinant Antibody (clone Ab-HKT288); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0391-FY-S(P) | Human Anti-CDH6 Recombinant Antibody; scFv Fragment (HPAB-0391-FY-S(P)) | FC, ELISA, Activ | Human scFv |
| HPAB-0392-FY-S(P) | Human Anti-CDH6 Recombinant Antibody; scFv Fragment (HPAB-0392-FY-S(P)) | FC, ELISA, Activ | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1300 | Anti-CDH6 Immunohistochemistry Kit | IHC |
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