Recombinant Anti-CEACAM3 Vesicular Antibody, EV Displayed (VS-0425-YC675)
CAT#: VS-0425-YC675
The Recombinant Anti-CEACAM3 Vesicular Antibody, EV Displayed (VS-0425-YC675) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CEACAM3-expressed cells or tissues. CEACAM3 is a member of the carcinoembryonic antigen-related cell adhesion molecules, involved in pathogen phagocytosis by the innate immune system.
Gene Expression
Normal Tissue
Figure 1 Colon
Enterocytes - Microvilli
Staining: Medium
Intensity: Moderate
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11041/27139_A_9_3.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11041/27139_A_7_8.jpg
RNA Expression
Figure 3 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000170956-CEACAM3
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CEACAM3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CEA cell adhesion molecule 3
- Introduction
- This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
- Alternative Names
- CD66d, CGM1
- Gene ID
- 1084
- UniProt ID
- P40198
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CEACAM3"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4489 | PE-Mamu-B*017:04/Human CEACAM3 (LPQHLFGYSW) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-YJ | Mouse Anti-CEACAM3 Recombinant Antibody (clone IOR-CEA1) | ELISA | Mouse IgG1 |
| VS3-WK750 | Mouse Anti-CEACAM3 Recombinant Antibody (clone ML01C02) | WB, ELISA | Mouse IgG1 |
| VS3-FY2665 | Mouse Anti-CEACAM3 Recombinant Antibody (VS3-FY2665) | WB, FC, ELISA | Mouse IgG |
| VS7-HM692 | Mouse Anti-CEACAM3 Recombinant Antibody (clone 8D5F12) | WB, FCM | Mouse IgG1 |
| VS7-HM693 | Mouse Anti-CEACAM3 Recombinant Antibody (clone 4F1H8) | WB, FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-YJ-S(P) | Mouse Anti-CEACAM3 Recombinant Antibody (clone IOR-CEA1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-YJ-F(E) | Mouse Anti-CEACAM3 Recombinant Antibody (clone IOR-CEA1); Fab Fragment | ELISA | Mouse Fab |
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