Mouse Anti-CEACAM3 Recombinant Antibody (VS3-FY2665)

CAT#: VS3-FY2665

This anti-CEACAM3 product is a mouse recombinant monoclonal antibody that has been carefully developed to target CEACAM3 protein, a calculated weight of 27 kDa. It shows capability of cross-reacting with human, rat. The monoclonal antibody can be used in the area of Mucinous Cystadenocarcinoma and Chronic Gonococcal Salpingitis. This monoclonal antibody can be used in Western Blot, Flow cytometry, ELISA.

Gene Expression
Figure 1 Colon Figure 2 Lymph node Figure 3 RNA cell line category: Not detected

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Carcinoembryonic antigen related cell adhesion molecule 3 of human and rat origins
  • Species Reactivity
  • Human, Rat
  • Applications
  • WB, FC, ELISA
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 27 kDa.
  • Related Disease
  • Mucinous Cystadenocarcinoma and Chronic Gonococcal Salpingitis

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/2000
    Flow cytometry: 1/50-1/200
    ELISA: 1/1000-1/10000

Target

  • Alternative Names
  • Carcinoembryonic Antigen Related Cell Adhesion Molecule 3; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3; Carcinoembryonic Antigen CGM1; CD66d Antigen; CD66D; CGM1
  • Sequence Similarities
  • Belongs to the immunoglobulin superfamily. CEA family.
  • Cellular Localization
  • Membrane
  • Post Translation Modifications
  • Tyrosine-phosphorylated in response to microbial binding.
    Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
    Glycosylation at Asn104 and Asn111
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 2 sites
  • Function
  • Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Secondary Antibody

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