Recombinant Anti-CXCR1 Vesicular Antibody, EV Displayed (VS-0425-YC34) (CAT#: VS-0425-YC34)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CXCR1

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-X-C motif chemokine receptor 1

• Biological Process
• Chemotaxis

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Introduction
• CXCR1 (C-X-C Motif Chemokine Receptor 1) is a Protein Coding gene. Diseases associated with CXCR1 include Human Immunodeficiency Virus Type 1 and Acute Pyelonephritis. Among its related pathways are Akt Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and interleukin-8 binding. An important paralog of this gene is CXCR2.

• Alternative Names
• CD181, CDw128a, CKR-1, CMKAR1, IL8RA

• Gene ID
• 3577

• UniProt ID
• P25024

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