Mouse Anti-CXCR1 Recombinant Antibody (clone SE2)
CAT#: VS11-QX56
This product is a recombinant mouse antibody that recognizes CXCR1. The SE2 antibody exhibits specificity towards IL8RA and does not display any cross-reactivity with IL8RB. This antibody can be used for the following applications: WB, FC, IHC.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows positivity in hematopoietic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_B_5_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_A_4_6.jpg
Normal Tissue
Figure 6 Spleen
Cells in red pulp Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31991/135676_B_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163464-CXCR1
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Specifications
- Immunogen
- BSA-conjugated peptide comprising of the IL-8RA N-terminal (amino acids 1-30).
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human CXCR1
- Species Reactivity
- Human
- Clone
- SE2
- Applications
- WB, FC, IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- CXCR1; C-X-C motif chemokine receptor 1; C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1
- Gene ID
- 3577
- UniProt ID
- P25024
- Long Name
- C-X-C chemokine receptor type 1
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Function
- Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CXCR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2338z | Mouse Anti-CXCR1 Recombinant Antibody (clone 41A1) | FC, IHC, Neut | Mouse IgG2a |
| MOB-2066MZ | Recombinant Mouse Anti-Human CXCR1 Antibody (clone 53806.222) | FC, IHC-Fr | Mouse antibody |
| VS-0723-WK101 | Human Anti-CXCR1 Recombinant Antibody (VS-0723-WK101) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-667CQ | Mouse Anti-CXCR1 Recombinant Antibody (clone 42705.111) | FC, Inhib | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-668CQ | Mouse Anti-CXCR1 Recombinant Antibody (clone CBL043) | FC, IHC, Neut | Mouse IgG2 |
| NEUT-669CQ | Mouse Anti-CXCR1 Recombinant Antibody (clone MM0221-7D22) | IHC-Fr, Neut, FC | Mouse IgG2a |
| NEUT-670CQ | Mouse Anti-CXCR1 Recombinant Antibody (clone CBL780) | FC, IHC, CyTOF®, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC34 | Recombinant Anti-CXCR1 Vesicular Antibody, EV Displayed (VS-0425-YC34) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1821 | Anti-CXCR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1822 | Anti-Human CXCR1 Immunohistochemistry Kit | IHC |
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