Recombinant Anti-CXCR3 Vesicular Antibody, EV Displayed (VS-0425-YC497) (CAT#: VS-0425-YC497)

• Application
• ELISA, FC, Inhib, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CXCR3

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-X-C motif chemokine receptor 3

• Biological Process
• Angiogenesis, Apoptosis, Chemotaxis

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Introduction
• CXCR3 (C-X-C Motif Chemokine Receptor 3) is a Protein Coding gene. Diseases associated with CXCR3 include Cutaneous Lupus Erythematosus and Pulmonary Sarcoidosis. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CXCR5.

• Alternative Names
• CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR

• Gene ID
• 2833

• UniProt ID
• P49682

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