Recombinant Anti-CXCR3 Vesicular Antibody, EV Displayed (VS-0425-YC497)
CAT#: VS-0425-YC497
The Recombinant Anti-CXCR3 Vesicular Antibody, EV Displayed (VS-0425-YC497) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CXCR3-expressed cells or tissues. CXCR3 is a chemokine receptor related to diseases like lupus and sarcoidosis. CXCR3 is involved in key signaling pathways and has a paralog known as CXCR5.
Gene Expression
Normal Tissue
Figure 1 Colon
Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45942/139633_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45942/139633_A_7_4.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45942/139633_A_5_6.jpg
Normal Tissue
Figure 4 High expression in lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45942/139633_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186810-CXCR3
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CXCR3
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-X-C motif chemokine receptor 3
- Biological Process
- Angiogenesis, Apoptosis, Chemotaxis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- CXCR3 (C-X-C Motif Chemokine Receptor 3) is a Protein Coding gene. Diseases associated with CXCR3 include Cutaneous Lupus Erythematosus and Pulmonary Sarcoidosis. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CXCR5.
- Alternative Names
- CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
- Gene ID
- 2833
- UniProt ID
- P49682
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Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| TAB-125MZ | Human Anti-CXCR3 Recombinant Antibody (TAB-125MZ) | FC | Human IgG |
| TAB-125MZ-F(E) | Human Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-125MZ-F(E)) | FC | Human Fab |
| TAB-126MZ-F(E) | Human Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-126MZ-F(E)) | FC | Human Fab |
| TAB-134MZ-F(E) | Human Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-134MZ-F(E)) | Chemotaxis assay | Human Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-136MZ | Anti-Human CXCR3 Recombinant Antibody (Ab1) | Inhib | Humanized antibody |
| TAB-137MZ | Anti-Human CXCR3 Recombinant Antibody (Ab2) | Inhib | Humanized antibody |
| TAB-138MZ | Anti-Human CXCR3 Recombinant Antibody (Ab3) | FC, Binding and chemotaxis assay | Humanized antibody |
| TAB-139MZ | Anti-Human CXCR3 Recombinant Antibody (Ab4) | FC, Binding and chemotaxis assay | Humanized antibody |
| TAB-140MZ | Anti-Human CXCR3 Recombinant Antibody (Ab5) | FC, Binding and chemotaxis assay | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-127MZ-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-127MZ-F(E)) | FC | Mouse Fab |
| TAB-129MZ-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-129MZ-F(E)) | FC | Mouse Fab |
| TAB-130MZ-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-130MZ-F(E)) | FC | Mouse Fab |
| TAB-131MZ-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-131MZ-F(E)) | FC | Mouse Fab |
| TAB-132MZ-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (TAB-132MZ-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-678CQ | Mouse Anti-CXCR3 Recombinant Antibody (clone G025H7) | FC, Block | Mouse IgG1, κ |
| NEUT-683CQ | Hamster Anti-Cxcr3 Recombinant Antibody (clone CXCR3-173) | FC, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-679CQ | Mouse Anti-CXCR3 Recombinant Antibody (clone 2Ar1) | ICC, IF, IHC-P, IHC-Fr, Neut, FC | Mouse IgG1 |
| NEUT-680CQ | Mouse Anti-CXCR3 Recombinant Antibody (clone CBL045) | FC, IHC, Neut | Mouse IgG1 |
| NEUT-681CQ | Mouse Anti-CXCR3 Recombinant Antibody (clone CBL794) | FC, IHC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-682CQ | Mouse Anti-CXCR3 Recombinant Antibody (clone MM0223-7K22) | IHC-Fr, Neut, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0888 | Hi-Affi™ Rabbit Anti-CXCR3 Recombinant Antibody (clone DS888AB) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378-YC-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (HPAB-0378-YC-F(E)) | FC | Mouse Fab |
| HPAB-0379-YC-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (HPAB-0379-YC-F(E)) | ELISA, FC, FuncS | Mouse Fab |
| HPAB-0380-YC-F(E) | Mouse Anti-CXCR3 Recombinant Antibody; Fab Fragment (HPAB-0380-YC-F(E)) | ELISA, FC, FuncS | Mouse Fab |
| HPAB-AP312-YC-F(E) | Human Anti-CXCR3 Recombinant Antibody; Fab Fragment (HPAB-AP312-YC-F(E)) | FC, Inhib | Chimeric (mouse/human) Fab |
| HPAB-AP313-YC-F(E) | Human Anti-CXCR3 Recombinant Antibody; Fab Fragment (HPAB-AP313-YC-F(E)) | FC, Inhib | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0405-CN | Rabbit Anti-CXCR3 Recombinant Antibody (clone JA61-33) | WB, IF, IP | Rabbit IgG |
| HPAB-AP312-YC | Human Anti-CXCR3 Recombinant Antibody (HPAB-AP312-YC) | FC, Inhib | Chimeric (mouse/human) IgG |
| HPAB-AP313-YC | Human Anti-CXCR3 Recombinant Antibody (HPAB-AP313-YC) | FC, Inhib | Humanized IgG |
| HPAB-AP314-YC | Human Anti-CXCR3 Recombinant Antibody (HPAB-AP314-YC) | FC, Inhib | Humanized IgG |
| HPAB-AP315-YC | Human Anti-CXCR3 Recombinant Antibody (HPAB-AP315-YC) | FC, Inhib | Chimeric (mouse/human) IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP312-YC-S(P) | Mouse Anti-CXCR3 Recombinant Antibody; scFv Fragment (HPAB-AP312-YC-S(P)) | FC, Inhib | Mouse scFv |
| HPAB-AP313-YC-S(P) | Human Anti-CXCR3 Recombinant Antibody; scFv Fragment (HPAB-AP313-YC-S(P)) | FC, Inhib | Humanized scFv |
| HPAB-AP314-YC-S(P) | Human Anti-CXCR3 Recombinant Antibody; scFv Fragment (HPAB-AP314-YC-S(P)) | FC, Inhib | Humanized scFv |
| HPAB-AP315-YC-S(P) | Mouse Anti-CXCR3 Recombinant Antibody; scFv Fragment (HPAB-AP315-YC-S(P)) | FC, Inhib | Mouse scFv |
| HPAB-AP316-YC-S(P) | Human Anti-CXCR3 Recombinant Antibody; scFv Fragment (HPAB-AP316-YC-S(P)) | FC, Inhib | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC277 | CytoStream™ Mouse Anti-CXCR3 Recombinant Antibody (VS13-YC277) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1824 | Anti-CXCR3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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