Recombinant Anti-DDR2 Vesicular Antibody, EV Displayed (VS-0425-YC220) (CAT#: VS-0425-YC220)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• DDR2

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Discoidin domain receptor tyrosine kinase 2

• Biological Process
• Osteogenesis

• Molecular Function
• Kinase, Receptor, Transferase, Tyrosine-protein kinase

• Cellular Localization
• Plasma membrane, Actin filaments

• Introduction
• This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.

• Alternative Names
• NTRKR3, TKT, TYRO10

• Gene ID
• 4921

• UniProt ID
• Q16832

Select a product category from the dropdown menu below to view related products.