Recombinant Anti-EREG Vesicular Antibody, EV Displayed (VS-0425-YC370) (CAT#: VS-0425-YC370)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• EREG

• Host Animal
• Human

• Antibody Isotype
• IgG1

• Species Reactivity
• Human, Cynomolgus

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Epiregulin

• Biological Process
• Angiogenesis, Differentiation

• Molecular Function
• Developmental protein, Growth factor, Mitogen

• Cellular Localization
• Vesicles, Cytosol

• Introduction
• This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

• Alternative Names
• ER

• Gene ID
• 2069

• UniProt ID
• O14944

Select a product category from the dropdown menu below to view related products.