Recombinant Anti-EREG Vesicular Antibody, EV Displayed (VS-0425-YC370)
CAT#: VS-0425-YC370
The Recombinant Anti-EREG Vesicular Antibody, EV Displayed (VS-0425-YC370) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EREG-expressed cells or tissues. The EREG is a peptide hormone part of the EGF family, which influences processes like cell proliferation and wound healing.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54373/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000124882-EREG
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EREG
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Epiregulin
- Biological Process
- Angiogenesis, Differentiation
- Molecular Function
- Developmental protein, Growth factor, Mitogen
- Cellular Localization
- Vesicles, Cytosol
- Introduction
- This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
- Alternative Names
- ER
- Gene ID
- 2069
- UniProt ID
- O14944
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "EREG"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2396z | Mouse Anti-EREG Recombinant Antibody (clone 43A4) | WB, IHC | Mouse IgG1 |
| PABL-084 | Mouse Anti-EREG Recombinant Antibody (clone 9E5) | ELISA, WB, FuncS | Mouse IgG |
| MOB-0693CT | Recombinant Mouse anti-Human EREG Monoclonal antibody (NN0376- 23Z5) | WB | |
| VS-0723-WK135 | Human Anti-EREG Recombinant Antibody (VS-0723-WK135) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-084 | Mouse Anti-EREG Recombinant Antibody (clone 9E5); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-084 | Mouse Anti-EREG Recombinant Antibody (clone 9E5); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-004WM | Anti-Human EREG Recombinant Antibody (EP27) | ELISA, Neut | Humanized Antibody |
| TAB-004WM-S(P) | Anti-Human EREG Recombinant Antibody scFv Fragment (EP27) | ELISA, Neut | Humanized Antibody |
| TAB-004WM-F(E) | Anti-Human EREG Recombinant Antibody Fab Fragment (EP27) | ELISA, Neut | Humanized Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-745CQ | Rat Anti-Ereg Recombinant Antibody (clone 6H12) | Neut, ELISA | Rat IgG2 |
| NEUT-746CQ | Rat Anti-Ereg Recombinant Antibody (clone CBL583) | ELISA, Neut | Rat IgG2a |
| NEUT-747CQ | Rat Anti-Ereg Recombinant Antibody (clone CBL870) | ELISA, Neut | Rat IgG |
| NEUT-748CQ | Rat Anti-Ereg Recombinant Antibody (clone RM0233-6H12) | Neut | Rat IgG2 |
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