Recombinant Anti-FCER1A Vesicular Antibody, EV Displayed (VS-0425-YC742)
CAT#: VS-0425-YC742
The Recombinant Anti-FCER1A Vesicular Antibody, EV Displayed (VS-0425-YC742) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FCER1A-expressed cells or tissues. FCER1A is the alpha subunit of the high-affinity IgE receptor, initiating allergic responses. This triggers mediator release upon allergen-bound IgE binding.
Gene Expression
Normal Tissue
Figure 1 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55526/130432_A_8_4.jpg
Normal Tissue
Figure 2 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55526/130432_A_7_5.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HEL)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179639-FCER1A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FCER1A
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Fc epsilon receptor Ia
- Molecular Function
- IgE-binding protein, Receptor
- Introduction
- The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
- Alternative Names
- FCE1A, FcepsilonRIalpha, FCERIA
- Gene ID
- 2205
- UniProt ID
- P12319
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Related Diseases
Asthma
Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2391z | Mouse Anti-FCER1A Recombinant Antibody (clone 29F11) | WB, ELISA, FC, IF, IHC, IP | Mouse IgG2b |
| FN-131CQ | Mouse Anti-FCER1A Recombinant Antibody (clone CRA1) | FuncS | Mouse IgG2b |
| FN-179CQ | Mouse Anti-FCER1A Recombinant Antibody (clone AER-37 (CRA1)) | FC, FuncS, ICC, IP | Mouse IgG2b, κ |
| HPAB-1142-FY | Mouse Anti-FCER1A Recombinant Antibody (clone 4-12C) | ELISA | Mouse IgG |
| FAMAB-0279JF | Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8) | IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-033WM | Human Anti-FCER1A Recombinant Antibody (TAB-033WM) | ELISA | Human IgG |
| TAB-033WM-S(P) | Human Anti-FCER1A Recombinant Antibody; scFv Fragment (TAB-033WM-S(P)) | ELISA | Human scFv |
| TAB-033WM-F(E) | Human Anti-FCER1A Recombinant Antibody; Fab Fragment (TAB-033WM-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-784CQ | Mouse Anti-FCER1A Recombinant Antibody (clone CBL651) | FC, CyTOF®, Neut | Mouse IgG2b |
| NEUT-785CQ | Hamster Anti-Fcer1a Recombinant Antibody (clone MAR-1) | FC, FuncS, Neut | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1142-FY-F(E) | Mouse Anti-FCER1A Recombinant Antibody (clone 4-12C); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1143-FY-F(E) | Mouse Anti-FCER1A Recombinant Antibody (clone 2-3A); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1144-FY-F(E) | Mouse Anti-FCER1A Recombinant Antibody (clone 5-1D); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1145-FY-F(E) | Mouse Anti-FCER1A Recombinant Antibody (clone 4-9E); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1146-FY-F(E) | Mouse Anti-FCER1A Recombinant Antibody (clone 7-3C); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1142-FY-S(P) | Mouse Anti-FCER1A Recombinant Antibody (clone 4-12C); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1143-FY-S(P) | Mouse Anti-FCER1A Recombinant Antibody (clone 2-3A); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0279JF-F(E) | Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1534WJ-F(E) | Human Anti-FCER1A Recombinant Antibody; Fab Fragment (clone CRA2) | ELISA, WB | Human Fab |
| HPAB-1535WJ-F(E) | Human Anti-FCER1A Recombinant Antibody; Fab Fragment (clone CRA4) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY119 | Human Anti-FCER1A scFv-Fc Chimera (VS-0425-FY119) | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2475 | Anti-Mouse FCER1A Immunohistochemistry Kit | IHC |
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