Recombinant Rabbit Anti-FOXA2 Detection Antibody (clone R87-3V-7) (CAT#: VS3-WK1833)
This antibody is a rabbit recombinant antibody against human FOXA2. It was developed by immunization of rabbit with recombinant human FOXA2 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R56-1R-9 and R87-3V-7 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R87-3V-7 can be used in ELISA analysis to identify human FOXA2.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66846/1304_B10_8_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66846/1304_B10_8_selected.jpg
Figure 2 High expression in stomach 1.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_5_1_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_5_1_selected.jpg
Figure 3 Low expression in kidney.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_7_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_7_5_val_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1388/3096_A_9_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (A549, HBEC3-KT, Hep G2, hTERT-HME1, OE19, PC-3, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125798-FOXA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125798-FOXA2
Specifications
- Immunogen
- Recombinant human FOXA2 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human FOXA2
- Species Reactivity
- Human
- Clone
- R87-3V-7
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Forkhead Box A2; Forkhead Box Protein A2; Transcription Factor 3B; HNF-3-Beta; HNF-3B; TCF-3B
- Gene ID
- 3170
- UniProt ID
- Q9Y261
- Long Name
- Forkhead Box A2
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylation on Thr-156 abolishes binding to target promoters and subsequent transcription activation upon insulin stimulation.
- Protein Refseq
- NP_068556.2
- Function
- Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FOXA2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3414z | Mouse Anti-FOXA2 Recombinant Antibody (clone 1F4) | ELISA, IF, IHC, IP, WB | Mouse IgG2a, κ |
| MOB-1058MZ | Recombinant Mouse Anti-Human FOXA2 Antibody (clone 2D8) | ELISA, IHC-P IP, WB | Mouse antibody |
| MRO-0600-CN | Rabbit Anti-FOXA2 Recombinant Antibody (clone JM10-64) | WB, IF | Rabbit IgG |
| ZG-0355J | Mouse Anti-FOXA2 Recombinant Antibody (ZG-0355J) | WB, IHC, ELISA | Mouse IgG |
| VS3-WK1832 | Recombinant Rabbit Anti-FOXA2 Capture Antibody (clone R56-1R-9) | ELISA | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1339 | Hi-Affi™ Rabbit Anti-FOXA2 Recombinant Antibody (clone DS1339AB) | WB, IP, ICC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-WK1833. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.