Recombinant Rabbit Anti-GAP43 Detection Antibody (clone R81-6N-1) (CAT#: VS3-WK1841)
This antibody is a rabbit recombinant antibody against human GAP43. It was developed by immunization of rabbit with recombinant human GAP43 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R81-6N-1 and R39-2C-4 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R81-6N-1 can be used in ELISA analysis to identify human GAP43.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13392/1510_B4_2_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13392/1510_B4_2_selected.jpg
Figure 2 Colon
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_A_8_3.jpg
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_A_8_3.jpg
Figure 3 High expression in cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_B_9_5.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15600/35117_B_9_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172020-GAP43
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172020-GAP43
Specifications
- Immunogen
- Recombinant human GAP43 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human GAP43
- Species Reactivity
- Human
- Clone
- R81-6N-1
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Growth Associated Protein 43; Axonal Membrane Protein GAP-43; Neural Phosphoprotein B-50; Neuron Growth-Associated Protein 43; Nerve Growth-Related Peptide GAP43; Calmodulin-Binding Protein P-57
- Gene ID
- 2596
- UniProt ID
- P17677
- Long Name
- Growth Associated Protein 43
- Sequence Similarities
- Belongs to the neuromodulin family.
- Cellular Localization
- Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse
- Post Translation Modifications
- Phosphorylated (By similarity).
Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity (By similarity).
Palmitoylated by ZDHHC3 (By similarity).
Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction (PubMed:14978216).
Deacylated by LYPLA2 (PubMed:21152083).
- Protein Refseq
- NP_001123536.1; NP_002036.1
- Function
- This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GAP43"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2432CT | Recombinant Mouse anti-Chicken GAP43 Monoclonal antibody (ZF370) | WB, ELISA, IHC-P, IHC-Fr | |
| MRO-0629-CN | Rabbit Anti-GAP43 Recombinant Antibody (clone CBACN-234) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-0052C | Mouse Anti-GAP43 Antibody (clone Mix) | WB, IHC-P, IF | Mouse IgG |
| VS4-WK188 | Mouse Anti-GAP43 Recombinant Antibody (VS4-WK188) | ELISA, WB, IHC | Mouse IgG |
| VS3-WK1840 | Recombinant Rabbit Anti-GAP43 Capture Antibody (clone R39-2C-4) | ELISA | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-WK1841. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, WB, BLI, SPR
Application: ELISA, Neut, FuncS
Application: ELISA, IP, WB, IHC, IF, FuncS
-3.jpg)
Application: WB, IHC, ELISA, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
-2.png)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
