Recombinant Anti-GPC1 Vesicular Antibody, EV Displayed (VS-0425-YC623)
CAT#: VS-0425-YC623
The Recombinant Anti-GPC1 Vesicular Antibody, EV Displayed (VS-0425-YC623) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GPC1-expressed cells or tissues. GPC1, a cell surface proteoglycan, plays roles in cell division and growth regulation as part of the glypican family.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30571/1715_D1_13_cr57fd06304494c_selected.jpg
Normal Tissue
Figure 2 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows moderate positivity in luminal membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30571/ihc_selected.jpg
Normal Tissue
Figure 3 Skin 1
High expression in skin 1
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70449/169210_B_8_1_val_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30571/64142_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30571/64142_A_8_3.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30571/64142_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000063660-GPC1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GPC1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glypican 1
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
- Alternative Names
- glypican
- Gene ID
- 2817
- UniProt ID
- P35052
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "GPC1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3467z | Mouse Anti-GPC1 Recombinant Antibody (clone 32H1) | WB, IP, IF | Mouse IgG1, κ |
| HPAB-0152-YJ | Mouse Anti-GPC1 Recombinant Antibody (HPAB-0152-YJ) | ELISA, WB | Mouse IgG1, κ |
| HPAB-0153-YJ | Mouse Anti-GPC1 Recombinant Antibody (HPAB-0153-YJ) | ELISA, WB | Mouse IgG1, κ |
| VS3-FY604 | Recombinant Rabbit Anti-GPC1 Antibody (clone R03-2E8) | WB, ICC, IF | Rabbit IgG |
| VS-0224-XY54 | Mouse Anti-GPC1 Recombinant Antibody (VS-0224-XY54) | ELISA, WB, IF, IP, IHC-P | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-033CN | Human Anti-GPC1 Recombinant Antibody (NS-033CN) | WB, IF | Human IgG1 |
| NS-033CN-F(E) | Human Anti-GPC1 Recombinant Antibody; Fab Fragment (NS-033CN-F(E)) | WB, IF | Human Fab |
| NS-033CN-S(P) | Human Anti-GPC1 Recombinant Antibody; scFv Fragment (NS-033CN-S(P)) | WB, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-YJ-S(P) | Mouse Anti-GPC1 Recombinant Antibody; scFv Fragment (HPAB-0152-YJ-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0153-YJ-S(P) | Mouse Anti-GPC1 Recombinant Antibody; scFv Fragment (HPAB-0153-YJ-S(P)) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-YJ-F(E) | Mouse Anti-GPC1 Recombinant Antibody; Fab Fragment (HPAB-0152-YJ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0153-YJ-F(E) | Mouse Anti-GPC1 Recombinant Antibody; Fab Fragment (HPAB-0153-YJ-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY60 | Mouse Anti-GPC1 scFv-Fc Chimera (VS-0125-FY60) | FC, IHC, IF | Mouse IgG2a, scFv-Fc |
| VS-0325-FY22 | Human Anti-GPC1 (clone K090-01a002) scFv-Fc Chimera | ADC, ELISA | Human IgG1, scFv-Fc |
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