Recombinant Anti-ITGA1 Vesicular Antibody, EV Displayed (VS-0425-YC383)
CAT#: VS-0425-YC383
The Recombinant Anti-ITGA1 Vesicular Antibody, EV Displayed (VS-0425-YC383) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGA1-expressed cells or tissues. The ITGA1 is the alpha 1 subunit of integrin receptors, forming a receptor with the beta 1 subunit for collagen and laminin, involved in cell adhesion and inflammation.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, SH-SY5Y, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213949-ITGA1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGA1
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit alpha 1
- Biological Process
- Cell adhesion
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Endoplasmic reticulum
- Introduction
- This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
- Alternative Names
- CD49a, VLA1
- Gene ID
- 3672
- UniProt ID
- P56199
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC383. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ITGA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1649z | Mouse Anti-ITGA1 Recombinant Antibody (clone 40D8) | FC, IHC, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-453CL | Human Anti-ITGA1 Recombinant Antibody (TAB-453CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-108 | Mouse Anti-ITGA1 Recombinant Antibody (clone AQC2) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-132 | Mouse Anti-ITGA1 Recombinant Antibody (clone mAb6) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-108 | Mouse Anti-ITGA1 Recombinant Antibody (clone AQC2); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-132 | Mouse Anti-ITGA1 Recombinant Antibody (clone mAb6); Fab Fragment | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-108 | Mouse Anti-ITGA1 Recombinant Antibody (clone AQC2); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-132 | Mouse Anti-ITGA1 Recombinant Antibody (clone mAb6); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356CQ | Human Anti-ITGA1 Recombinant Antibody (TAB-356CQ) | ELISA, FC | Human IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-357CQ | Human Anti-ITGA1 Recombinant Antibody (TAB-357CQ) | ELISA, FC | Human IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356CQ-S(P) | Human Anti-ITGA1 Recombinant Antibody; scFv Fragment (TAB-356CQ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-357CQ-S(P) | Human Anti-ITGA1 Recombinant Antibody; scFv Fragment (TAB-357CQ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356CQ-F(E) | Human Anti-ITGA1 Recombinant Antibody; Fab Fragment (TAB-356CQ-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2124MZ | Recombinant Mouse Anti-Human ITGA1 Antibody (clone 0.U.74) | ELISA, ICC | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0292MZ | Chicken Anti-ITGA1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-121 | Recombinant Mouse Anti-Integrin alpha 1 Antibody (AQC2) | WB, ELISA, Neut, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-188 | Mouse Anti-ITGA1 Recombinant Antibody (PABX-188) | WB, ELISA, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-121-F (E) | Recombinant Mouse Anti-Integrin alpha 1 Antibody Fab Fragment (AQC2) | WB, ELISA, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-188-F (E) | Mouse Anti-ITGA1 Recombinant Antibody; Fab Fragment (PABX-188-F (E)) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1541CQ | Recombinant Mouse Anti-ITGA1 Antibody (5E8D9) | Neut, ICC, IF | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1764-FY | Human Anti-ITGA1 Recombinant Antibody (clone 3.40) | ELISA, FuncS | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1764-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 3.40); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1765-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 2.19); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1766-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 7.22); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1764-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 3.40); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1765-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 2.19); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1766-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 7.22); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3611 | Anti-ITGA1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3612 | Anti-Rat ITGA1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, Cyt, Stim, PP, Agonist
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, WB, BLI, SPR
Application: WB, ELISA, FuncS
Application: ELISA, SPR, Inhib, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
