Recombinant Mouse Anti-KRT6A Antibody (VS4-CJ11) (CAT#: VS4-CJ11)
This mouse anti-KRT6A antibody is a product that recognizes human KRT6A. The immunogen of this antibody is a synthesized peptide derived from human Cytokeratin 6. The mAb has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/1715_H5_3_cr57fd30536afd1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/1715_H5_3_cr57fd30536afd1_selected.jpg
Figure 2 IF staining of human cell line hTCEpi
(Immunofluorescent staining of human cell line hTCEpi shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/1790_E10_1_selected.jpg
(Immunofluorescent staining of human cell line hTCEpi shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/1790_E10_1_selected.jpg
Figure 3 IHC staining of human vulva/anal skin
(Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_8_selected.jpg
(Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_8_selected.jpg
Figure 4 IHC staining of human oral mucosa
(Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/ihc_selected.jpg
(Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/ihc_selected.jpg
Figure 5 Esophagus
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_1.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_1.jpg
Figure 6 RNA cell line category: Cell line enriched (hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000205420-KRT6A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000205420-KRT6A
Specifications
- Immunogen
- Synthesized peptide derived from human Cytokeratin 6
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human KRT6A
- Species Reactivity
- Human
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
Target
- Alternative Names
- K6A; KRT6D; Keratin type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; K6A; Type-II keratin Kb6; allergen Hom s 5; KRT6B; K6B; KRTL1; Keratin type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; K6B; Type-II keratin Kb10; KRT6C; KRT6E; Keratin type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; K6C; Type-II keratin Kb12; K6D; PC3
- Gene ID
- 3853
- UniProt ID
- P02538
- Long Name
- Keratin 6A
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Intermediate filament, Keratin
- Protein Refseq
- NP_005545.1
- Function
- Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Recommended Products
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1991 | Hi-Affi™ Recombinant Rabbit Anti-KRT6A Monoclonal Antibody (DS1991AB) | WB, FC, IP, IHC | IgG |
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