Recombinant Anti-LAMP1 Vesicular Antibody, EV Displayed (VS-0425-YC666) (CAT#: VS-0425-YC666)
The Recombinant Anti-LAMP1 Vesicular Antibody, EV Displayed (VS-0425-YC666) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LAMP1-expressed cells or tissues. LAMP1 is a membrane glycoprotein providing carbohydrate ligands for selectins, potentially playing a role in tumor metastasis.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Ihc staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows strong granular positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14750/34136_A_5_5_selected.jpg
(Immunohistochemical staining of human urinary bladder shows strong granular positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14750/34136_A_5_5_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity(granular pattern) in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/ihc_selected.jpg
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity(granular pattern) in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_B_9_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_B_9_5.jpg
Figure 4 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_4.jpg
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_4.jpg
Figure 5 Pancreas
(Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_1_3.jpg
(Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_1_3.jpg
Figure 6 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_7_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_7_5.jpg
Figure 7 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_6_6.jpg
Figure 8 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_8.jpg
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185896-LAMP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185896-LAMP1
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LAMP1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Monkey
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Lysosomal associated membrane protein 1
- Biological Process
- Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Introduction
- The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
- Alternative Names
- CD107a
- Gene ID
- 3916
- UniProt ID
- P11279
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-611 | Recombinant Anti-human LAMP1 Antibody | ELISA, WB, FC, FuncS | IgG |
| HPAB-0035-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0035-LSX) | ELISA, IHC, ADCC | Human IgG |
| HPAB-0036-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0036-LSX) | ELISA, IHC, ADCC, FuncS | Human IgG |
| HPAB-0037-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0037-LSX) | ELISA, IHC | Chimeric (mouse/human) IgG |
| HPAB-0038-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0038-LSX) | ELISA, IHC, FC, ADCC, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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