LAMP1

Lysosomal associated membrane protein 1 (LAMP-1), also known as lysosomal associated membrane glycoprotein 1 and CD107a (differentiation cluster 107a), is a protein encoded by the LAMP1 gene in the human body. The human LAMP1 gene is located on the long arm (q) of chromosome 13 and is located in region 3, band 4 (13q34).Lysosomal-associated membrane protein 1 is a glycoprotein from the lysosomal-associated membrane glycoprotein family. LAMP-1 glycoprotein is a type I transmembrane protein, expressed at high or moderate levels in at least 76 different normal tissue cell types. It is mainly located on the lysosomal membrane, and plays a role in providing carbohydrate ligand to selectin. CD107a has also been shown to be a degranulation marker for lymphocytes (eg CD8 + and NK cells). and may play a role in the differentiation and metastasis of tumor cells.