Recombinant Anti-LGR6 Vesicular Antibody, EV Displayed (VS-0425-YC561) (CAT#: VS-0425-YC561)
The Recombinant Anti-LGR6 Vesicular Antibody, EV Displayed (VS-0425-YC561) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LGR6-expressed cells or tissues. LGR6 is a member of the G protein-coupled receptor superfamily, crucial for binding ligand through its characteristic leucine-rich repeats.

(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/159_F6_2_selected.jpg

(Immunohistochemical staining of human colon shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/ihc_selected.jpg

(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/23734_B_8_5.jpg

(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/23734_A_8_4.jpg

(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/23734_A_7_5.jpg

(Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8556/23734_A_6_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000133067-LGR6
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LGR6
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leucine rich repeat containing G protein-coupled receptor 6
- Biological Process
- Wnt signaling pathway
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane, Nucleoplasm
- Introduction
- This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding.
- Alternative Names
- FLJ14471
- Gene ID
- 59352
- UniProt ID
- Q9HBX8
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LGR6"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1819z | Mouse Anti-LGR6 Recombinant Antibody (clone 38B7) | WB, ELISA, IF, IP | Mouse IgG1, κ |
HPAB-0467-YJ | Mouse Anti-LGR6 Recombinant Antibody (clone Mu2C15) | ELISA, WB, ICC, FC, IHC | Mouse IgG1 |
VS3-FY1732 | Rabbit Anti-LGR6 Recombinant Antibody (clone R09-8B5) | WB, IHC-Fr, IHC-P, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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