Rabbit Anti-LGR6 Recombinant Antibody (clone R09-8B5) (CAT#: VS3-FY1732)
The R09-8B5 recombinant monoclonal antibody is able to identify human LGR6. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IHC-F, IHC-P, ICC/IF. The antibody has the positive detection of LGR6 protein by western blot analysis of GPCR LGR6 in K562, C6, 3T3, Hela lysates.
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WB
Figure 1 Anti-LGR6 Antibody (VS3-FY1732) in WB.
The GPCR LGR6 expression in K562, C6, 3T3, Hela lysates were detected using the anti-GPCR LGR6 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human GPCR LGR6
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat LGR6
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-8B5
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
- MW
- The calculated weight of the target protein is approximately 104 kDa, while the observed molecular weight stands at 104 kDa.
- Related Disease
- Myxedema and Hair Follicle Neoplasm
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- GPCR; VTS20631
- Gene ID
- 59352
- UniProt ID
- Q9HBX8
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Disulfide bond
Glycoprotein
- Protein Refseq
- XP_005245461.1; XP_011508140.1; XP_011508141.1; XP_011508142.1; XP_011508143.1
- Function
- Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1819z | Mouse Anti-LGR6 Recombinant Antibody (clone 38B7) | WB, ELISA, IF, IP | Mouse IgG1, κ |
| HPAB-0467-YJ | Mouse Anti-LGR6 Recombinant Antibody (clone Mu2C15) | ELISA, WB, ICC, FC, IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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