Recombinant Anti-LRRC32 Vesicular Antibody, EV Displayed (VS-0425-YC334)
CAT#: VS-0425-YC334
The Recombinant Anti-LRRC32 Vesicular Antibody, EV Displayed (VS-0425-YC334) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LRRC32-expressed cells or tissues. The LRRC32 is a membrane protein with leucine-rich repeats, with chromosomal alterations linked to various pathologies.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line ASC TERT1
Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55775/1774_D8_12_cr5950fd0cdc360_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (ASC diff, ASC TERT1, HSkMC, HUVEC TERT2, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137507-LRRC32
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LRRC32
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leucine rich repeat containing 32
- Molecular Function
- Growth factor binding
- Cellular Localization
- Nucleoplasm
- Introduction
- This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.
- Alternative Names
- D11S833E, GARP
- Gene ID
- 2615
- UniProt ID
- Q14392
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Downloadable Resources
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Datasheet
MSDS
COA
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| TAB-045CQ-F(E) | Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (TAB-045CQ-F(E)) | ELISA, FC, WB | Mouse Fab |
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| TAB-046CQ-F(E) | Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (TAB-046CQ-F(E)) | ELISA, FC, WB | Human Fab |
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| HPAB-2836LY | Mouse Anti-LRRC32 Recombinant Antibody (HPAB-2836LY) | ELISA | Mouse IgG |
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| HPAB-2837LY | Mouse Anti-LRRC32 Recombinant Antibody (HPAB-2837LY) | ELISA | Mouse IgG |
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| HPAB-2838LY | Human Anti-LRRC32 Recombinant Antibody (HPAB-2838LY) | ELISA | Chimeric (Rat/Human) IgG |
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| HPAB-2839LY | Human Anti-LRRC32 Recombinant Antibody (HPAB-2839LY) | ELISA | Chimeric (Rat/Human) IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2840LY | Human Anti-LRRC32 Recombinant Antibody (HPAB-2840LY) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
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| HPAB-2836LY-S(P) | Mouse Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2836LY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2837LY-S(P) | Mouse Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2837LY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2838LY-S(P) | Rat Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2838LY-S(P)) | ELISA | Rat scFv |
| CAT | Product Name | Application | Type |
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| HPAB-2839LY-S(P) | Rat Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2839LY-S(P)) | ELISA | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2840LY-S(P) | Human Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2840LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2836LY-F(E) | Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2836LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2837LY-F(E) | Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2837LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2838LY-F(E) | Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2838LY-F(E)) | ELISA | Chimeric (Rat/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2839LY-F(E) | Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2839LY-F(E)) | ELISA | Chimeric (Rat/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2840LY-F(E) | Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2840LY-F(E)) | ELISA | Human Fab |
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