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LRRC32

Anti-LRRC32 Products

Mouse Anti-LRRC32 Recombinant Antibody (TAB-045CQ) (TAB-045CQ)
- Species Reactivity: Human, Cynomolgus
- Type: Mouse IgG
- Application: ELISA, FC, WB
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Human Anti-LRRC32 Recombinant Antibody (TAB-046CQ) (TAB-046CQ)
- Species Reactivity: Human, Cynomolgus
- Type: Human IgG1
- Application: ELISA, FC, WB
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Human Anti-LRRC32 Recombinant Antibody; scFv Fragment (TAB-046CQ-S(P)) (TAB-046CQ-S(P))
- Species Reactivity: Human, Cynomolgus
- Type: Human scFv
- Application: ELISA, FC, WB
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Mouse Anti-LRRC32 Recombinant Antibody (HPAB-2836LY) (HPAB-2836LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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Mouse Anti-LRRC32 Recombinant Antibody (HPAB-2837LY) (HPAB-2837LY)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody (HPAB-2838LY) (HPAB-2838LY)
- Derivation: Chimeric (Rat/Human)
- Species Reactivity: Human
- Type: Chimeric (Rat/Human) IgG
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody (HPAB-2839LY) (HPAB-2839LY)
- Derivation: Chimeric (Rat/Human)
- Species Reactivity: Human
- Type: Chimeric (Rat/Human) IgG
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody (HPAB-2840LY) (HPAB-2840LY)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody (HPAB-2841LY) (HPAB-2841LY)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (TAB-046CQ-F(E)) (TAB-046CQ-F(E))
- Species Reactivity: Human, Cynomolgus
- Type: Human Fab
- Application: ELISA, FC, WB
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Mouse Anti-LRRC32 Recombinant Antibody (clone 4D3) (VS-0224-XY79)
- Species Reactivity: Human, Mouse (weak)
- Type: Mouse IgG1
- Application: ELISA, FC, Block
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Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (TAB-045CQ-F(E)) (TAB-045CQ-F(E))
- Species Reactivity: Human, Cynomolgus
- Type: Mouse Fab
- Application: ELISA, FC, WB
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Mouse Anti-LRRC32 Recombinant Antibody; scFv Fragment (TAB-045CQ-S(P)) (TAB-045CQ-S(P))
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scFv
- Application: ELISA, FC, WB
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Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2836LY-F(E)) (HPAB-2836LY-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2837LY-F(E)) (HPAB-2837LY-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2838LY-F(E)) (HPAB-2838LY-F(E))
- Derivation: Chimeric (Rat/Human)
- Species Reactivity: Human
- Type: Chimeric (Rat/Human) Fab
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2839LY-F(E)) (HPAB-2839LY-F(E))
- Derivation: Chimeric (Rat/Human)
- Species Reactivity: Human
- Type: Chimeric (Rat/Human) Fab
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2840LY-F(E)) (HPAB-2840LY-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; Fab Fragment (HPAB-2841LY-F(E)) (HPAB-2841LY-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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Mouse Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2836LY-S(P)) (HPAB-2836LY-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2837LY-S(P)) (HPAB-2837LY-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Rat Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2838LY-S(P)) (HPAB-2838LY-S(P))
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA
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Rat Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2839LY-S(P)) (HPAB-2839LY-S(P))
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2840LY-S(P)) (HPAB-2840LY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-LRRC32 Recombinant Antibody; scFv Fragment (HPAB-2841LY-S(P)) (HPAB-2841LY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Recombinant Anti-LRRC32 Vesicular Antibody, EV Displayed (VS-0425-YC334) (VS-0425-YC334)
- Species Reactivity: Human, Cynomolgus
- Target: LRRC32
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Extravillous trophoblasts, Hepatic stellate cells, Endothelial cells, Adipocytes, Smooth muscle cells, Sertoli cells)

Immune cell specificity

Immune cell enhanced (T-reg)

Cell line specificity

Group enriched (ASC diff, ASC TERT1, HSkMC, HUVEC TERT2, U-2197)

Interaction

Interacts with TGFB1; associates via disulfide bonds with the Latency-associated peptide chain (LAP) regulatory chain of TGFB1, leading to regulate activation of TGF-beta-1 (PubMed:19651619, 22278742). Interacts with TGFB2 (PubMed:19651619). Interacts with TGFB3; associates via disulfide bonds with the Latency-associated peptide chain (LAP) regulatory chain of TGFB3, leading to regulate activation of TGF-beta-3 (By similarity). Interacts with LAPTM4B; decreases TGFB1 production in regulatory T-cells (PubMed:26126825).

Molecular function

Growth factor binding

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