Recombinant Anti-LRRN1 Vesicular Antibody, EV Displayed (VS-0425-YC126)
CAT#: VS-0425-YC126
The Recombinant Anti-LRRN1 Vesicular Antibody, EV Displayed (VS-0425-YC126) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LRRN1-expressed cells or tissues. The LRRN1 is predicted to act upstream of or within positive regulation of synapse assembly and is located in the membrane. It serves as a biomarker for stomach cancer.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
High expression. RNA expression: 7.2 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_B_8_5_val_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lymph node
Low expression. RNA expression: 0.3 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_8_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11071/29441_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (AF22, CAPAN-2, HAP1, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175928-LRRN1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LRRN1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leucine rich repeat neuronal 1
- Cellular Localization
- Endoplasmic reticulum, Basal body, Golgi apparatus, Centriolar satellite
- Introduction
- Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in membrane. Predicted to be active in extracellular matrix and extracellular space. Biomarker of stomach cancer.
- Alternative Names
- FIGLER3
- Gene ID
- 57633
- UniProt ID
- Q6UXK5
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LRRN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-522MZ | Anti-Human LRRN1 Recombinant Antibody (TB0777#281-6 (N1mAb)) | ELISA, FC | |
| TAB-522MZ-S(P) | Anti-Human LRRN1 Recombinant Antibody scFv Fragment (TB0777#281-6 (N1mAb)) | ELISA, FC | |
| TAB-522MZ-F(E) | Anti-Human LRRN1 Recombinant Antibody Fab Fragment (TB0777#281-6 (N1mAb)) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0617WJ | Mouse Anti-LRRN1 Recombinant Antibody (clone 2.5.1) | ELISA, WB | Mouse IgG |
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